in 1987 decided to produce an edited version of the minutes of the society from its inception in 1908. The result is a narrative that is surprisingly readable and records faithfully what the medical fraternity in Bath were thinking and writing papers about, the clinical cases they presented and how they conducted their affairs. The book which runs to 248 pages was obviously a labour of love for...

We demonstrate that a finite bath fluctuation theorem of the Crooks type holds for systems that have been thermalized via weakly coupling them to a bath with energy independent finite specific heat. We show that this theorem reduces to the known canonical and microcanonical fluctuation theorems in the two respective limiting cases of infinite and vanishing specific heat of the bath. The result ...

t is possible to extract work from a quantum-mechanical system whose dynamics is governed by a time-dependent cyclic Hamiltonian. An energy bath is required to operate such a quantum engine in place of the heat bath used to run a conventional classical thermodynamic heat engine. The effect of the energy bath is to maintain the expectation value of the system Hamiltonian during an isoenergetic p...

We investigate the interaction of a particle with a finite-size bath represented by a set of independent linear oscillators with frequencies that fall within a finite bandwidth. We discover that when the oscillators have particular frequency distributions, the finite-size bath behaves much as an infinite-size bath exhibiting dissipation properties and thus allowing irreversible energy absorptio...

Introduction In this paper we explain recent changes in urban structures and CBD functions in Vienna by entrepreneurial decisions to locate office buildings. The decisions to site office facilities are seen, in turn, as dependent on quantitative and qualitative demand for office space, and on the particular spatial conditions of the local office supply. The question we are dealing with in this ...

BACKGROUND Liposomes have been successfully used as delivery vehicles for anticancer drugs. Both sonication and microfluidic technologies have been used to produce liposomes. The combination of the two methods was evaluated in this study. MATERIALS AND METHODS The microfluidic devices, mainly comprising micro-dispensers and a sonicator, were used to produce liposomal nanoparticles. Sonication...

Several common metabolites and drugs in the serum in of patients with inflammatory, infectious, autoimmune, immunodeficient, neoplastic, and toxicant-induced diseases can produce artifactual suppression of the [methyl-3H]-thymidine assay, which is widely used to evaluate lymphocyte responsiveness. We have developed a sensitive, semiautomated, fluorescence-enhancement assay in which true immunos...

The objectives of our study were to prepare and evaluate a biodegradable nanoparticulate system of Letrozole (LTZ) intended for breast cancer therapy. LTZ loaded poly(lactide-co-glycolide) nanoparticles (LTZ-PLGA-NPs) were prepared by emulsion-solvent evaporation method using methylene chloride and polyvinyl alcohol. Percentage of drug (with respect to polymer) was selected as formulation varia...