Benign skull lesions are routinely encountered in clinical practice. The aim of this review is to describe the Computed tomography (CT) findings of solitary benign parietal lesions. Benign parietal bone lesions can exist in patients with history of cancer. Metastasis to the calvarium is rare compared to other sites in the body and primary skull tumors are even rarer. This is the second report o...

Early and accurate detection of bone tumors and their staging are important since some of them are highly malignant. Intraoperative pathological consultation in bone tumors and tumor-like conditions is quite complex; however, it allows improvement in prognosis and limb salvage. Present study was conducted on 52 patients who underwent surgical procedure after clinical and radiological diagnosis ...

Primary bone tumors are uncommon and this has certainly contributed to the scarcity of data about their relative frequency, and to the limited understanding of the risk factors. Overall, bone sarcomas account for 0.2% of all malignancies, and the adjusted incidence rate for all bone and joint malignancies is 0.9 per 100,000 persons per year, while the 5-year overall survival rate is 67.9%. The ...

Aneurysmal bone cysts (ABCs) are benign bony lesions frequently accompanied by multiple cystic lesions and aggressive bone destruction. They are relatively rare lesions, representing only 1% of bone tumors. The pathogenesis of ABCs has yet to be elucidated. In the present study, a series of 22 cases of primary and secondary ABC from patients treated in Department of Orthopedic Surgery, Kagoshim...

Sclerostin (SOST) is an extracellular Wnt signaling antagonist which negatively regulates bone mass. Despite this, the expression and function of SOST in skeletal tumors remain poorly described. Here, we first describe the immunohistochemical staining pattern of SOST across benign and malignant skeletal tumors with bone or cartilage matrix (n=68 primary tumors). Next, relative SOST expression w...

Background . Due to diversity of cancer, the functional role galectin-3 is rather controversial; however, for many types neoplasms, marker acts as a tumor growth promoter. Aim To perform comparative analysis levels in blood serum healthy individuals and patients with benign, borderline, malignant bone tumors divided into two age groups (under over 18 years age) based on main clinical morphologi...

Giant cell tumor of the bone (GCTOB) is a relatively uncommon tumor of the bone. It is characterized by the presence of multinucleated giant cells. Giant-cell tumor of the bone accounts for 4-5% of primary bone tumors and ∼20% of benign bone tumors. Giant cell tumors of the hand are rare, accounting for only 2-4% of all giant cell tumors. Giant cell tumor (GCT) of the bones of the hand has some...

UNLABELLED Osteochondroma, which is also known as exostosis, is the most common benign bone tumor. Although foot and hand surgeons frequently encounter the subungual exostosis, exostoses commonly localize to other areas of the skeleton as well. In this review, we describe the clinical and diagnostic imaging characteristics of benign bone tumors and, in particular, the osteochondroma and its sur...

Dermoid cysts are common orbital developmental tumors in childhood. They account for 3 to 9% of primary tumors. considered be congenital, but not all them diagnosed at birth. benign choristomas that arise from sequestration ectoderm along the lines embryonic fusion mesodermal processes destined bone. In most cases, lesion is close zygomatic-frontal suture leading a superotemporal subcutaneous m...