Background: Beta-thalassemia major is a severe and lethal hemolytic anemia. Regular transfusion is necessary for avoidance of its complications but it may end to cardiac involvement secondary to iron overload. Angiotensin converting enzyme inhibitors (ACEIs) are useful medications even in early stages of heart failure. We studied the effects of two common ACEIs on improvement of heart function ...

The concentrations of beta-lactoglobulin was measured in the sera of 47 preterm an term neonates during the first few days of life under standardised conditions after feeding with a cows' milk'based formula. Preterm neonates, particularly those of less than 33 weeks' gestation, had higher serum concentrations of beta-lactoglobulin than term neonates given an equivalent mild feed. Prior feeding ...

We report the demonstration of a heat-fraction-limited CW Yb:YAG laser operating near 77 K with output at 1029 nm, pumped with a diffraction-limited room-temperature CW Nd:YAG laser operating at 946 nm. With a 50% reflectivity outcoupler, the average threshold absorbed pump power was 18.8 mW and the average slope efficiency 91.9%, close to the heat-fraction limited value of 91.5%. Average optic...

To understand luminous AGNs in the z < 1 universe, the ASCA AGN samples are the best at present. Combining the identified sample of AGNs from ASCA Large Sky Survey and Medium Sensitivity Survey, the sample of hard X-ray selected AGNs have been expanded up to 108 AGNs above the flux limit of 10 erg s cm in the 2–10 keV hard X-ray band. We discuss the fraction of absorbed AGNs in the hard X-ray s...

328 words Introduction: 420 words Discussion: 1403 words Abbreviations: AUC, area under the curve; CL, clearance, Cmax, maximum concentration; F, bioavailability; Fa, fraction absorbed; Fg, fraction escaping gut wall elimination; Fh, fraction escaping hepatic elimination; HLM, human liver microsomes; PK, pharmacokinetics, SD, standard deviation; tmax, time to reach Cmax. This article has not be...

UNLABELLED An object-oriented software system is described for estimating internal emitter absorbed doses using a set of computer modules operating within a personal computer environment. The system is called the Radionuclide Treatment Planning and Absorbed Dose Estimation System (RTDS). It is intended for radioimmunotherapy applications, although other forms of internal emitter therapy may als...

Although there is strong evidence to suggest that flavonoid consumption is beneficial to human health, the extent to which flavonoids are absorbed and the mechanisms involved are controversial. Contrary to common dogma, we previously demonstrated that quercetin 4'-beta-glucoside, the predominant form of the most abundant dietary flavonoid, quercetin, was not absorbed across Caco-2 cell monolaye...