Objective: Treatment of a recalcitrant case of Kimura’s disease (KD) is described. Lesions recurred after injection of betamethasone, but responded well to radiation therapy using a Varian 21EX linear accelerator. A literature review and discussion of efficiency and safety issues is included. Method: A 53-year-old female with KD of the right cheek was treated with intramuscular injection of bet...

Objectives: This study was undertaken to compare the efficacy and safety of fexofenadine with chlorpheniramine and betamethasone in allergic rhinitis. Methods: This was a prospective observational study on 75 patients of allergic rhinitis. They were randomly divided into 3 groups of 25 patients each for receiving fexofenadine, chlorpheniramine and betamethasone respectively. Improvement of symp...

Evaluation of the effects of betamethasone on patients with intrauterine growth restriction in couple with preeclampsia is not well studied. This study was designed to assess and compare the changes of Doppler flow in maternal, fetal and placental arteries in singleton pregnancies complicated by IUGR and preeclampsia which are at 24-34 weeks of gestation after betamethasone therapy. This prospe...

The effects of two topical nasal preparations on human nasal ciliary beat frequency in vitro and on nasal mucociliary clearance in vivo were investigated. Betamethasone and betamethasone with neomycin drops were found to be ciliotoxic when ciliated epithelium was exposed to them in vitro, mainly owing to the effects of the preservatives benzalkonium chloride and thiomersal. The nasal mucociliar...

AIMS To compare the relative antiinflammatory potency and safety of topical diclofenac-gentamicin with betamethasone-neomycin following strabismus surgery. METHODS A single centre, single observer, prospective, randomised, and double masked clinical trial of 25 children undergoing bilateral symmetrical horizontal strabismus surgery was carried out. One eye received diclofenac-gentamicin and t...

We report the case of a 58-year-old woman who was referred to our hospital due to frequent bloody mucus diarrhea. She was diagnosed with cap polyposis based on typical endoscopic and histological findings. Colonoscopy revealed multiple, reddish, mucus-capped polypoid lesions from the rectum to the sigmoid colon. A pathological examination revealed that the polyps were covered by erosive and inf...

We describe 5 cases of immediate-type reactions to systemic corticosteroids observed during the last 2 decades in boys aged 2, 4, 8, 9, and 10 years. Symptoms ranged from generalized urticaria and angioedema to anaphylactic shock immediately after administration. Oral betamethasone was implicated in 2 cases, oral prednisolone in 2 cases, and intravenous prednisolone in 1 case. The parents of pa...

OBJECTIVE To compare the efficacy of intralesional triamcinolone and topical betamethasone in the management of localized alopecia areata. STUDY DESIGN A randomized trial. PLACE AND DURATION OF STUDY Dermatology OPD, PNS Shifa Hospital, Karachi, from January to June 2013. METHODOLOGY Patients aged 18 - 50 years with localized alopecia areata were included in the study. Exclusion criteria ...

Prostate cancer occurs more frequently among older males and such elderly individuals often have chronic underlying disorders for which various drugs are administered for treatment. The levels of prostate-specific antigen (PSA), a widely used prostate cancer marker, are influenced by a number of drugs, such as non-steroidal anti-inflammatory drugs and statins. In the present study, the drugs pr...

STUDY OBJECTIVE To investigate whether betamethasone decreases the incidence of postoperative nausea/vomiting (PONV) and reduces postoperative pain following partial mastectomy. DESIGN Prospective randomized, double-blinded study. SETTING Operating room and Postanesthesia Care Unit of a university hospital. PATIENTS 80 ASA physical status 1 and 2 women scheduled for elective breast cancer...