DRUGS AND UPTAKE OF 32p BY ERYTHROCYTES 533' 5. Sodium salicylate and sodium thiopentone depressed the 32p uptake of 2:3-diphosphoglycerate and adenosine triphosphate to a greater extent than they depressed the 32P exchange of inorganic phosphate and hexose monophosphate. These agents do not depress 32p uptake by inhibiting triose phosphate dehydrogenase, for neither drug had any effect on glyc...

Anwar, M. A., M. Schwab, L. Poston, and P. W. Nathanielsz. Betamethasone-mediated vascular dysfunction and changes in hematological profile in the ovine fetus. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H1137–H1143, 1999.—Glucocorticoid administration to fetal sheep induces a sustained systemic blood pressure rise and an associated increase in femoral vascular resistance. We utilized a smal...

Glucocorticoid administration to fetal sheep induces a sustained systemic blood pressure rise and an associated increase in femoral vascular resistance. We utilized a small vessel myograph to compare isometric vascular responses of small femoral arterial branches from fetal sheep infused intravenously with either betamethasone or vehicle in vivo from 128 days gestation. Changes in hematological...

1. The thermal denaturation of DNA from rat liver was studied spectrophotometrically. In sodium phosphate buffers denaturation led to a single-stranded form having, at 25 degrees , about 25% of the hypochromism of the intact double helix. 2. The hypochromism of the denatured form was the same in 1mm- as in 10mm-sodium phosphate buffer and was scarcely affected by reaction with formaldehyde. The...

PURPOSE The aim of this study was to compare the efficacy and patient tolerance of two bowel preparations for colonoscopy. METHODS Three hundred twenty-three consecutive patients undergoing colonoscopy were randomly assigned to receive either oral sodium phosphate, or 2 liters of polyethylene glycol solution preceded by the stimulant laxative bisacodyl. Patients were asked to record the effec...

Everolimus (EVR) is an orally-administered rapamycin analog that selectively inhibits the mammalian target of rapamycin (mTOR) kinase (mainly mTORC1 and likely mTORC2) and the related signaling pathway. mTOR is a serine/threonine protein kinase regulating multiple important cellular functions; dysfunction of mTOR signaling has also been implicated in the pathophysiology of several neurological,...

PURPOSE To investigate the effect and safety of benzalkonium chloride on transscleral drug delivery in the rabbit after continuous intrascleral administration. METHODS Betamethasone 21-phosphate (BP) aqueous solutions, with or without benzalkonium chloride (BAK), were continuously administered to albino rabbit sclera with an osmotic pump for 1 week. The BP concentrations in the aqueous humor,...

PURPOSE To characterize the cornea of individuals with Thygeson's superficial punctate keratitis (TSPK) at the cellular level by laser confocal biomicroscopy. METHODS Both corneas of three patients with TSPK referred to Yamaguchi University Hospital were imaged with a laser confocal biomicroscope. Morphological changes were evaluated for each layer of the cornea. RESULTS The number of Lange...

recent studies show that synthetic glucocorticoids alter testicular homeostasis, in this regard, the influence of betamethasone as a glucocorticoid widely used on histological changes, epididymal sperm counts and fertility was explored in male mice. the study sample (50 mice) was allocated to 3 treatment groups, placebo and a control group. control group was no injected. only normal saline was ...

Correction for 'The transformation from amorphous iron phosphate to sodium iron phosphate in sodium-ion batteries' by Yao Liu et al., Phys. Chem. Chem. Phys., 2015, 17, 22144-22151.