BACKGROUND Chlorhexidine gluconate (CHG) has been proven to be effective in preventing and controlling biofilm formation. At the same time, an increase in calculus formation is known as one of considerable side effects. The purpose of this study was to investigate whether mineral deposition preceding a calculus formation would occur at an early stage after the use of CHG using an in vitro saliv...

BACKGROUND BoneXpert is an automated method to calculate bone maturation and bone health index (BHI) in children with juvenile idiopathic arthritis (JIA). Cartilage thickness can also be seen as an indicator for bone health and arthritis damage. The objective of this study was to evaluate the relation between cartilage thickness, bone maturation and bone health in patients with JIA. METHODS P...

Monitoring the bioenergetics of leucocytes is now emerging as an important approach in translational research to detect mitochondrial dysfunction in blood or other patient samples. Using the mitochondrial stress test, which involves the sequential addition of mitochondrial inhibitors to adherent leucocytes, we have calculated a single value, the Bioenergetic Health Index (BHI), which represents...

The polysaccharide capsule of Streptococcus pneumoniae defines over ninety serotypes, which differ in their carriage prevalence and invasiveness for poorly understood reasons. Recently, an inverse correlation between carriage prevalence and oligosaccharide structure of a given capsule has been described. Our previous work suggested a link between serotype and growth in vitro. Here we investigat...

Biofilms formed by Staphylococcus aureus is a serious complication to the use of medical implants. A central part of the pathogenesis relies on S. aureus' ability to adhere to host extracellular matrix proteins, which adsorb to medical implants and stimulate biofilm formation. Being coagulase positive, S. aureus furthermore induces formation of fibrin fibers from fibrinogen in the blood. Conseq...

INTRODUCTION One of the main goals of endodontic treatment is to decrease the harboring bacteria within the root canal system and dentinal tubules. This experimental study attempted to investigate the antibacterial efficacy of three root canal irrigants in the presence and absence of smear layer (SL). METHODS AND MATERIALS A total of 210 sound extracted human single-rooted teeth were prepared...

Periodontitis is a microorganism that invades the subgingival area, thereby triggering an inflammatory response of periodontal tissue. Fusobacterium nucleatum one most abundant gram-negative bacilli colonizing plaque and closely associated with disease. The aim study was to calculate inhibition snail mucus against bacteria concentrations 12.5%, 25%, 50%, 100%. This used laboratory experimental ...

The aim of the present study was to assess transcriptomic response L. monocytogenes during co-culture with three S. cerevisiae strains. For this purpose, BHI broth inoculated 7 log CFU?mL?1 serotype 4b strain LQC 15257, isolated from a strawberry sample and 4 strains Y32, Y34 Y37, spontaneous olive fermentation. Sampling took place after 24 48 h incubation at 5 20 °C. RNA extracted, stabilized ...

New technical and scientific developments have been advocated to promote the success of the endodontic treatment. In addition to rotary and reciprocating systems, irrigating solution agitation has been suggested and passive ultrasonic irrigation (PUI) is the most used. OBJECTIVE To evaluate, in vitro, the effect of ultrasound streaming (US) in the disinfection of flattened root canal systems ...

BACKGROUND AND PURPOSE Several methods are being used to assess cerebral vasomotor reactivity (CVR), including transcranial Doppler (TCD) sonography and blood oxygenation level-dependent functional magnetic resonance imaging (fMRI). The aim was to assess the correlation of TCD and fMRI in the CVR assessment. METHODS Study group consisted of 28 patients (24 males, 4 females; aged 30-82, mean 6...