نتایج جستجو برای: bile duct ligation
تعداد نتایج: 76491 فیلتر نتایج به سال:
The present study investigated the effect of colchicine and trimethylcolchicinic acid on liver fibrosis induced by common bile duct ligation in albino rats. Bile duct ligated rats showed cirrhosis where liver architecture completely distorted with diffused fibrosis and generation of abnormal nodules. Hepatocytes with nuclear changes and highly proliferated bile ductules were also detected. Alph...
A new experimental model of acute pancreatitis in the rat has been devised. It consists of a closed duodenal loop into which infected bile is injected under pressure; intestinal continuity is maintained by a plastic tube passed through the loop. Histological and biochemical evidence of acute pancreatitis in the rat model is presented. The model has been compared with that of Nevalainen and with...
BACKGROUND Peroxisome proliferators-activated receptor alpha (PPARalpha) activation modulates cholesterol metabolism and suppresses bile acid synthesis. This study aims to evaluate the effect of short-term administration of fenofibrate, a PPARalpha agonist, on proinflammatory cytokines, apoptosis, and hepatocellular damage in cholestasis. METHODS Forty male Wistar rats were randomly divided i...
BACKGROUND Avulsion of cystic duct during laparoscopic cholecystectomy (LC) is not a common intraoperative complication, but may be encountered by any laparoscopic surgeon. Surgeons are rarely familiar with management of this condition. METHODS Patients with gall stone related problems who were scheduled for LC at the minimal invasive surgery unit of a tertiary referral hospital during a 5 ye...
Cholestasis is associated with hypercholesterolemia and appearance of the abnormal lipoprotein X (LpX) in plasma. Using mice with a disrupted Mdr2 gene, we tested the hypothesis that LpX originates as a biliary lipid vesicle. Mdr2-deficient mice lack Mdr2 P-glycoprotein, the canalicular translocator for phosphatidylcholine, and secrete virtually no phospholipid and cholesterol in bile. Bile duc...
The influence of bile acids on adenosine 3',5'-phosphate-induced intestinal secretion was studied in mice. Bile flow was stopped by ligation of the common bile duct, and secretion was induced in ligated loops of the small intestine. The decrease of bile led to inhibition of hypersecretion after challenge with heat-labile enterotoxins from Vibrio cholerae and Escherichia coli, as well as with pr...
Lymphatic drainage leads to a significant stimulation of both the cholesterol 7 alpha-hydroxylase and HMG-CoA reductase activity in rats (Björkhem et al. 1978. Biochem. Biophys. Res. Commun. 85: (532-540). This finding was confirmed here and it was also shown that ligation of the lymph duct leads to a similar but less pronounced effect. Ligation of the lymph duct or lymph fistulation of bile du...
OBJECTIVES This study aimed to establish a novel non-binding, reversible rat model of acute cholangitis of the severe type (ACST). MATERIALS AND METHODS Twenty-six rats were randomly divided into the sham-operated group (n=13) and the ACST group (n=13). All rats were intubated with a modified catheter through the external jugular vein. The ACST model was established by ligation of the distal ...
carcinoid tumors of the bile duct are rare. despite cholangiocarcinoma, they grow more slowly and generally occur in younger patients and females. these tumors have a better prognosis and more disease-free survival. we present the case of a 25-year- old male with common bile duct (cbd) carcinoid tumor misdiagnosed as cholangiocarcinoma.
introduction: given the importance of identifying common bile duct diameter in diseases diagnoses and being different in different races, this paper aimed to investigate the relationship between the diameter of the common bile duct and demographic factors and drug addiction in patients who referred to the imaging department of imam reza hospital in birjand during the year 1391-1392. methods: th...
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