نتایج جستجو برای: bio nanoparticle

تعداد نتایج: 90938  

2013
Peter H. Hemmerich Anna H. von Mikecz

Understanding of nanoparticle-bio-interactions within living cells requires knowledge about the dynamic behavior of nanomaterials during their cellular uptake, intracellular traffic and mutual reactions with cell organelles. Here, we introduce a protocol of combined kinetic imaging techniques that enables investigation of exemplary fluorochrome-labelled nanoparticles concerning their intracellu...

2012
Archita Biswas Aparna Gomes Jayeeta Sengupta Poulami Datta Santiswarup Singha Anjan Kr Dasgupta Antony Gomes

Nano-medical approaches to develop drugs have attracted much attention in different arenas to design nanoparticle conjugates for better efficacy of the potential bio-molecules. A group of promising candidates of this category would be venom-toxins of animal origin of potential medicinal value. Traditional systems of medicine as well as folklores mention the use of venom-toxins for the treatment...

2017
Adrian A Walsh

Gold nanoparticles have been available for many years as a research tool in the life sciences due to their electron density and optical properties. New applications are continually being developed, particularly in nanomedicine. One drawback is the need for an easy, real-time quantitation method for gold nanoparticles so that the effects observed in in vitro cell toxicity assays and cell uptake ...

2013
James A. Milton Samson Patole Huabing Yin Qiang Xiao Tom Brown Tracy Melvin

Although strategies for the immobilization of DNA oligonucleotides onto surfaces for bioanalytical and top-down bio-inspired nanobiofabrication approaches are well developed, the effect of introducing spacer molecules between the surface and the DNA oligonucleotide for the hybridization of nanoparticle-DNA conjugates has not been previously assessed in a quantitative manner. The hybridization e...

2012
Christian A. Ruge Ulrich F. Schaefer Jennifer Herrmann Julian Kirch Olga Cañadas Mercedes Echaide Jesús Pérez-Gil Cristina Casals Rolf Müller Claus-Michael Lehr

The peripheral lungs are a potential entrance portal for nanoparticles into the human body due to their large surface area. The fact that nanoparticles can be deposited in the alveolar region of the lungs is of interest for pulmonary drug delivery strategies and is of equal importance for toxicological considerations. Therefore, a detailed understanding of nanoparticle interaction with the stru...

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