Citation Leonard, Effendi et al. " Opportunities in metabolic engineering to facilitate scalable alkaloid production. The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Abstract 1 2 Numerous drugs and drug precursors in the current pharmacopoeia 3 originate from plant sources. The limited yield of bioactive compounds in 4 plant...

Horse grame has a long history of usage as an antihypertensive and treatment for diseases infections. Along with lipids other types proteins, many steroidal, alkaloid, glycoside chemicals were present in horse gram significant bioactive components. Rich source milk protein, vitamins A C, nutrients. It belongs to the Lamiaceae family 15 different genetic species that are primarily grown Asia Afr...

Acacia nilotica, indigenously known as ‘Babool’ of family Leguminosae has many traditional and ethnobotanical uses. All the parts tree are important seeds most abundantly available which rich in different phytochemicals. Thus, aim this study was qualitative quantitative analysis phytochemicals evaluation antioxidant activity nilotica seed along with their viz. cotyledon endosperm a potential so...

This study set out to evaluate the phytochemical composition of Erythrophleum suaveolens leaves extract and its fungicidal attributes on Aspergillus flavus isolated from maize seeds. The E. were collected Gwagalada, Abuja, Nigeria, subjected soxhlet extraction with methanol chloroform as solvents determine bioactive compounds in compared water crude extract. Different concentrations plant extra...

The alkaloid spectra of Datura innoxia plants grown in Egypt and Bulgaria were investigated by GC-MS. Thirty-eight alkaloids were detected in the roots, leaves and fruits of the plants. Five new alkaloids for D. innoxia are reported. Alkaloid spectra of Egyptian and Bulgarian plants differ significantly in respect to their alkaloid composition and main alkaloids accumulated in the plant organs.

Variation in plant defensive profiles can be affected by environmental factors, genetic factors, and their interactions, and different feeding guilds may have different responses to variation in defenses. Here we present results of a factorial breeding design in Lupinus arboreus from three sites of origin to determine how parental effects, population differences, and environmental effects influ...

The predominant alkaloids in lotus leaves are aporphine alkaloids. These are the most important active components and have many pharmacological properties, but little is known about their biosynthesis. We used digital gene expression (DGE) technology to identify differentially-expressed genes (DEGs) between two lotus cultivars with different alkaloid contents at four leaf development stages. We...

Elektrokinetické vlastnosti zmesí minerálov Elektroforetický rozptyl svetla (ELS) je nová experimentálna technika umožňujúca merať spectrum elektroforetickej pohyblivosti alebo zeta (ξ) potenciálu skupiny častíc. Toto spectrum odráža distribúciu náboja a čiastočne distribúciu rozmeru týchto častíc. Avšak, okrem modálnej hodnoty napr. zeta potenciálu častíc rovnakého druhu, z ELS spektra môžeme ...

It is desirable and necessary to reexamine the influences of stock andl scion oIn alkaloid synthesis and transformation using plants which behave differently witlh respect to alkaloid formation (4). Experiments were conducted in the greenhouse for 3 years in an attempt to separate the effects of root, or stock, from those of the top, or scioIn, on alkaloid synthesis and transformation. Some of ...