نتایج جستجو برای: biofunctionalization

تعداد نتایج: 250  

2009
Timothy A. Petrie Catherine D. Reyes Kellie L. Burns Andrés J. García

Integrin-mediated cell adhesion to biomolecules adsorbed onto biomedical devices regulates device integration and performance. Because of the central role of integrin-fibronectin (FN) interactions in osteoblastic function and bone formation, we evaluated the ability of FN-inspired biomolecular coatings to promote osteoblastic differentiation and implant osseointegration. Notably, these biomolec...

2012
Martina Schleicher Jan Hansmann Bentsian Elkin Petra J. Kluger Simone Liebscher Agnes J. T. Huber Olaf Fritze Christine Schille Michaela Müller Katja Schenke-Layland Martina Seifert Heike Walles Hans-Peter Wendel Ulrich A. Stock

In vivo self-endothelialization by endothelial cell adhesion on cardiovascular implants is highly desirable. DNA-oligonucleotides are an intriguing coating material with nonimmunogenic characteristics and the feasibility of easy and rapid chemical fabrication. The objective of this study was the creation of cell adhesive DNA-oligonucleotide coatings on vascular implant surfaces. DNA-oligonucleo...

Journal: :Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 2012
Jerry C Chang Oleg Kovtun Randy D Blakely Sandra J Rosenthal

The ability to efficiently visualize protein targets in cells is a fundamental goal in biological research. Recently, quantum dots (QDots) have emerged as a powerful class of fluorescent probes for labeling membrane proteins in living cells because of breakthrough advances in QDot surface chemistry and biofunctionalization strategies. This review discusses the increasing use of QDots for fluore...

Journal: :Advanced Healthcare Materials 2021

Surface modification of biomaterials is a promising approach to control biofunctionality while retaining the bulk biomaterial properties. Perlecan major proteoglycan in vascular basement membrane that supports low levels platelet adhesion but not activation. Thus, perlecan bioactive for blood-contacting applications. This study furthers mechanistic understanding interactions with by establishin...

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