While there has been a longstanding interest in stability of non-isothermal reactors there has only recently developed a comparable interest in the dynamics of onen isothermal reactors with complex chemical reaction networks. In the recent literature there has been paid particular attention to the study of biological reaction systems which might exhibit sustained oscillations (biological clocks...

The circadian timing system provides a temporal structure across an organism to modulate and synchronize biological function. The mammalian circadian system is composed of many individual clocks. Circadian clocks are found in individual cells that have to be synchronized by a central pacemaker. This pacemaker can be viewed as a managing director who coordinates temporal physiology and behavior ...

Patients suffering from neuropsychiatric disorders often exhibit a loss of regulation of their biological rhythms which leads to altered sleep/wake cycle, body temperature rhythm and hormonal rhythms. Whereas these symptoms have long been considered to result from the pathology of the underlying disease, increasing evidence now indicates that the circadian system may be more directly involved i...

Biological clocks are intrinsic time-keeping systems that regulate behavior and physiological functions in most living organisms. Recent works in this area have addressed possible molecular links between the endogenous circadian clock and cell cycle regulation. In this review, by addressing how circadian clocks can interfere with the cell cycle and how the disruption of the circadian rhythm may...

BACKGROUND Biomarkers of biological aging - DNA methylation age (DNAm age) and leukocyte telomere length (LTL)- correlate strongly with chronological age across the life course. It is, however, unclear how these measures of cellular wear and tear are associated with muscle strength and functional capacity, which are known to decline with older age and are associated with mortality. We investiga...

13 Wolff, S., and H. E. Luippold, "The Biochemical Aspects of Chromosome Rejoining," in Progress in Radiobiology, eds. J. S. Mitchell, B. E. Holmes, and C. L. Smith (Edinburgh: Oliver and Boyd, 1956), p. 217. 14 Beatty, A. V., and J. W. Beatty, Amer. Jour. Bot., 46, 317 (1959). 15 Thornton, N. C., Contrib. Boyce Thompson Inst., 5, 371 (1933). 16 Jackson, W. A., and N. T. Coleman, Plant and Soil...

There, he and his American wife moved into a newly been used to argue that entrainment depends on an built house on Portland Place, a broad street near the opsin in mammals. On this side, the argument leans center of London. Portraits of Thomas and Margaret still heavily on two classes of photoresponses that persist frame the fireplace in one of the house's largest rooms, in mice genetically de...