نتایج جستجو برای: biomarker validation

تعداد نتایج: 227799  

Journal: :International Journal of Biological Sciences 2009

2007
Elise C. Kohn Nilofer Azad Christina Annunziata Amit S. Dhamoon Gordon Whiteley

Novel technologies are now being advanced for the purpose of identification and validation of new disease biomarkers. A reliable and useful clinical biomarker must a) come from a readily attainable source, such as blood or urine, b) have sufficient sensitivity to correctly identify affected individuals, c) have sufficient specificity to avoid incorrect labeling of unaffected persons, and d) res...

Journal: :Molecular & cellular proteomics : MCP 2010
José M A Moreira Gita Ohlsson Pavel Gromov Ronald Simon Guido Sauter Julio E Celis Irina Gromova

It is becoming increasingly clear that no single marker will have the sensitivity and specificity necessary to be used on its own for diagnosis/prognosis of tumors. Interpatient and intratumor heterogeneity provides overwhelming odds against the existence of such an ideal marker. With this in mind, our laboratory has been applying a long term systematic approach to identify multiple biomarkers ...

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