Affecting approximately eight million people in the US, bipolar disorder represents a significant public health concern. Over 90% of individuals diagnosed with the disorder report multiple affective episodes across their lifetime, and recent data suggest that patients with bipolar disorder will remain symptomatically ill for roughly 50% of their lives. Consistent with this chronic course, bipol...

objective: bipolar disorder is a severe mental disorder, and its prevalence is around 1% to 2%. despite a vast literature around bipolar disorder, the reasons of its nonadherence and rehospitalization is still obscure. several symptoms of bipolar disorder include changes in activity level, cognitive abilities, speech, and vegetative functions, such as sleep, sexual activity, as well as aggressi...

Abstract Background Bipolar disorder is associated with circadian disruption and a high risk of suicidal behavior. In previous exploratory study patients bipolar I disorder, we found that history suicide attempts was differences between winter summer levels solar insolation. The purpose this to confirm finding using international data from 42% more collection sites 25% countries. Methods Data a...

This paper seeks to raise awareness of the impact and burden of bipolar depression and the need to improve its recognition and management in clinical practice. Bipolar depression is commonly misdiagnosed as unipolar depression and consequently, patients may receive inappropriate treatment that could potentially worsen symptoms. The Mood Disorder Questionnaire (MDQ) is a useful screening tool fo...

BACKGROUND The prevalence rate of completed suicide in bipolar disorder is estimated to be as high as 19%. Social factors or influences, such as stigmatisation and family conflict, contribute to the development of suicidal ideation in clinical and non-clinical populations. Yet, there is a lack of studies examining suicidality from a psychosocial perspective in people who experience bipolar diso...

Manic-depression (contemporary bipolar disorder) has been known since the era of Hippocrates and Areteus. However, in light of data accumulated over the last 20 years, our understanding of this disorder has changed significantly. Kraepelin's contribution, which emphasized generally favorable outcome for this illness, needs to be revised in part due to chronic and complex clinical pictures beyon...

Family history and traumatic experiences are factors linked to bipolar disorder. It is known that the lifetime risk of bipolar disorder in relatives of a bipolar proband are 5-10% for first degree relatives and 40-70% for monozygotic co-twins. It is also known that patients with early childhood trauma present earlier onset of bipolar disorder, increased number of manic episodes, and more suicid...

This study aims to explore the association between bipolar disorder and the risk of gout using a nationwide population-based dataset. We used the 1996-2006 data from the Taiwan National Health Insurance Research Database. The study cohort comprised 24,262 patients who had visited outpatient departments for the treatment of bipolar disorder in the year 2000. A total of 121,310 enrollees matched ...

The Kraepelinian dichotomy sees schizophrenia and bipolar disorder as two distinctly separate diseases each with its own pathogenesis and disease process. This study looks at the difference between patients with schizophrenia and bipolar disorder in terms of suicidal behaviour. Both schizophrenia and bipolar disorder have been identified as significant risk factors for suicide, while bipolar an...