نتایج جستجو برای: birdshot choroidipathy

تعداد نتایج: 152  

Journal: :Human molecular genetics 2014
Jonas J W Kuiper Jessica Van Setten Stephan Ripke Ruben Van 'T Slot Flip Mulder Tom Missotten G Seerp Baarsma Laurent C Francioli Sara L Pulit Carolien G F De Kovel Ninette Ten Dam-Van Loon Anneke I Den Hollander Paulien Huis in het Veld Carel B Hoyng Miguel Cordero-Coma Javier Martín Victor Llorenç Bharti Arya Dhanes Thomas Steven C Bakker Roel A Ophoff Aniki Rothova Paul I W De Bakker Tuna Mutis Bobby P C Koeleman

Birdshot chorioretinopathy (BSCR) is a rare form of autoimmune uveitis that can lead to severe visual impairment. Intriguingly, >95% of cases carry the HLA-A29 allele, which defines the strongest documented HLA association for a human disease. We have conducted a genome-wide association study in 96 Dutch and 27 Spanish cases, and 398 unrelated Dutch and 380 Spanish controls. Fine-mapping the pr...

2017
Joanna Brydak-Godowska Joanna Gołębiewska Monika Turczyńska Joanna Moneta-Wielgoś Agnieszka Samsel Piotr K. Borkowski Michał Ciszek Agnieszka Płonecka-Rodzoch Aleksandra Kuźnik-Borkowska Joanna Ciszewska Elżbieta Makomaska-Szaroszyk Lidia B. Brydak Dariusz Kęcik

BACKGROUND The aim of this study was to assess the clinical course and distinctive features of different white dot syndromes (WDS) in patients attending the Ophthalmology Department, Medical University of Warsaw in the years 1995-2015. MATERIAL AND METHODS Sixty-two (62) patients (43 females and 19 males), aged 18 to 77 years, referred with a WDS were included in this prospective study, with ob...

2014
Zeina Haddad Ashvini Reddy

BACKGROUND Birdshot chorioretinitis (BSCR) is a rare ocular inflammatory disorder associated with HLA-A29 and characterized by bilateral choroidal lesions, vitritis, macular edema, and retinal vasculitis. Ocular inflammation associated with HLA-B27 is typically a recurrent, unilateral, acute anterior uveitis (AAU) that is frequently associated with ankylosing spondylitis (AS). To date, there ar...

Journal: :JPMA. The Journal of the Pakistan Medical Association 2012
Muhammad Ishaq Jibran Sualeh Muhammad Khalid Mahmood

OBJECTIVE To find the causes and characteristics of uveitis and its subtypes among Pakistani population, and to create awareness that early diagnosis and treatment of uveitis requires a multi-disciplinary approach. METHODS The retrospective study involved 98 diagnosed uveitis patients. Data was analysed regarding associated systemic diseases, infections, ocular syndromes, anatomical localisat...

2016
Loren S. Jack Aniruddha Agarwal Yasir Jamal Sepah Quan Dong Nguyen

BACKGROUND The purpose of this paper is to study the spatial agreement between visual field defects and ultra-wide field (UWF) fundus autofluorescence (FAF) in patients with birdshot chorioretinopathy (BSCR). The study is a retrospective, cross-sectional analysis of a university uveitis practice. Eight (8) eyes of five (5) patients with BSCR were included. Inclusion criteria were ability to fix...

Journal: :Acta ophthalmologica 2017
Rupesh Agrawal Nichole Joachim Ling-Jun Li Jiaying Lee Aniruddha Agarwal Dawn A Sim Pearse A Keane Gerald Liew Carlos E Pavesio

PURPOSE Birdshot chorioretinopathy (BCR) is a potentially blinding ocular disorder involving the retinal vasculature and choroid without any systemic manifestations. The objective of the study was to describe vascular calibre changes in BCR and analyse the possibility of this optical biomarker for staging and monitoring disease activity in BCR. METHODS This retrospective case-control study at...

Journal: :Ocular immunology and inflammation 2016
Audrey-Elodie Mercier Emmanuel Ribeiro Jean-François Korobelnik Marie-Noëlle Delyfer Marie-Bénédicte Rougier

PURPOSE To assess the efficacy of anti-TNF alpha (TNF-α) therapy in patients with non-infectious uveitis. METHODS This was a monocentric observational study of 21 patients with non-infectious uveitis treated with anti-TNF-alpha. The primary endpoint was the control of ocular inflammation. The secondary endpoints included the study of macular thickness and visual acuity, changes in other treat...

2014
Marilita M Moschos Nikolaos S Gouliopoulos Christos Kalogeropoulos

PURPOSE Uveitis is the inflammation of the uveal tract, which usually also affects the retina and vitreous humor. The electrophysiological examination is an objective ocular examination that includes the electroretinogram, visual evoked potentials, the electrooculogram, the multifocal electroretinogram, and multifocal visual evoked potentials. Our aim is to review the literature of the use of t...

Journal: :Ophthalmology 1998
K Chatzistefanou N N Markomichelakis W Christen M Soheilian C S Foster

OBJECTIVE This study aimed to describe the clinical characteristics of uveitis presenting de novo in the elderly. DESIGN The study design was a description of a retrospectively identified case series. PARTICIPANTS A population of 138 patients (209 eyes) with uveitis beginning after age 60 was analyzed. RESULTS Uveitis in the elderly accounted for 10.4% of the authors' uveitis population. ...

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