PURPOSE To monitor changes in corneal structure and level of inflammatory mediators in tears of myopic patients following orthokeratology (OK) and laser in situ keratomileusis (LASIK). METHODS Sixty-two myopic subjects were analyzed in this prospective study. Thirty-two had worn Paragon CRT contact lenses and 30 underwent standard LASIK. Thirty-two control subjects were also recruited. Pachom...

PURPOSE To evaluate the visual and refractive outcome for four wavefront-guided surface ablation (WGSA) techniques (LASEK, LASEK flap-off [LASEK FO], Epi-LASIK, and Epi-LASIK flap-off [Epi-LASIK FO]) in a large myopic population. METHODS This retrospective review included 1000 myopic eyes (spherical equivalent [SE] -1.0 to -8.0 diopters [D]) treated with WGSA (VISX STAR S4 with IR) using four...

PURPOSE To evaluate visual performance during concentrated visual work in patients wearing soft contact lenses or after LASIK. METHODS Thirty-one eyes of 17 patients who had worn soft contact lenses before LASIK were examined by the following tests immediately and 10 seconds after eye opening: 1) functional visual acuity, which is defined as visual acuity measured after prolonged eye opening ...

PURPOSE A time-varying statistical model was proposed to predict the risk of regression toward myopia after laser in situ keratomileusis (LASIK) and to identify significant predictors within a time frame. METHODS A total of 615 eyes of 311 patients derived from a retrospective cohort who underwent LASIK in 2003 were analyzed. Refraction outcomes were recorded at 1 day, 1 week, and 1, 3, 6, 9,...

PURPOSE To compare 1-year results: safety, efficacy, refractive and keratometric stability, of femtosecond myopic laser-assisted in situ keratomileusis (LASIK) with and without concurrent prophylactic high-fluence cross-linking (CXL) (LASIK-CXL). METHODS We studied a total of 155 consecutive eyes planned for LASIK myopic correction. Group A represented 73 eyes that were treated additionally w...

To the Editor: We were interested to read the recent study by Huang and co-authors (Huang D, Sur S, Seffo F, Mesiler DM, Krueger RR. Surgically-induced astigmatism after laser in situ keratomileusis for spherical myopia. J Refract Surg 2000;16:515-518) regarding the possible effect of the LASIK flap on surgically-induced astigmatism. In that study, the authors found that a superior hinge produc...

purpose : to assess and to compare stromal and endothelial changes at the cellular level in patients who had photorefractive keratectomy (prk) and laser in situ keratomileusis (lasik) using in vivo confocal microscopy methods : in this semiexperimental study, 32 eyes of 16 patients (4 males and 12 females) with low to moderate myopia [-1.00 to -4.50 diopters (d)] or low to moderate myopic astig...

WAVEFRONT-guided photorefractive keratectomy (PRK) induces fewer higher-order aberrations than wavefrontguided LASIK, while the latter induces fewer higher order aberrations than conventional or optimised LASIK, suggest the preliminary results of two new studies presented at the XXIII Congress of the ESCRS. “In my practice, I employ wavefront guided technology in every patient that is eligible,...

Purpose: To compare the postoperative results of Epi-LASIK and photorefractive keratectomy-mitomycin (PRK-mitomycin) in patients with moderate to high myopia Methods: For this double-blind clinical trial, samples were randomly selected among those subjects above 20 years of age who were visited for myopia correction and had a spherical equivalent between -4 to -8 D. We randomly performed PRK-mi...