INTRODUCTION Inherited defects in RUNX1 are important causes of platelet function disorders. AIM Our goals were to evaluate RUNX1-related platelet disorders among individuals evaluated for uncharacterized, inherited platelet function disorders and test a proof of concept that bleeding risks could be quantitatively estimated for typical families with an inherited platelet function disorder. ...

Bleeding is the most common adverse event after percutaneous coronary intervention (PCI). It can occur either as a direct complication of the index procedure or spontaneously during the antithrombotic treatment for secondary prevention. Hemorrhagic complications significantly impact the prognosis independently from their timing and have been associated with a poorer quality of life [1]. In addi...

We propose a new framework for Conley index theory. The main feature of our approach is that we do not use the notion pairs. introduce, instead, notions compactifiable subsets and neighbourhoods, formulate prove basic results in theory using these notions. treat both discrete time case continuous case.

INTRODUCTION Although duodenal diverticula are common, periampullary duodenal diverticula are rare. Periampullary duodenal diverticula are usually asymptomatic and may be difficult to diagnose and treat. However, they may present with massive bleeding, requiring prompt diagnosis. CASE PRESENTATION We report the case of a 71-year-old Asian woman with bleeding from a periampullary duodenal dive...

BACKGROUND Perioperative antiplatelet agents potentially increase bleeding after non-ST-segment elevation (NSTE) acute coronary syndromes (ACS). The protease-activated receptor 1 antagonist vorapaxar reduced cardiovascular events and was associated with increased bleeding versus placebo in NSTE ACS, but its efficacy and safety in noncardiac surgery (NCS) remain unknown. We aimed to evaluate isc...

Aim To evaluate the effectiveness on tissue response of the new nutritional supplement made of oligomeric proanthocyanidins in induced gingivitis after 21 days of use. Material and Methods A prospective, double-blind, randomized, controlled clinical trial was carried out on 20 patients; it is divided into an experimental group and a control group after fulfilling the selection criteria. Patie...

Background The poor hygiene of peri-implant tissues causes inflammation at tissue-implant interface, which may impair the rehabilitation success. The aim of this study was to evaluate the influence of external hexagon and Morse taper implants on peri-implant health in patients wearing mandibular overdentures for 1 year. Materials and Methods A total of 46 implants were evaluated, 28 external ...

A 59-year-old woman with a history of von Recklinghausen's disease (VRD) suffered sudden chest pain. Enhanced chest computed tomography showed massive hemothorax, but no evidence of tumors or an obvious bleeding point in the thorax. After we had ensured a stable hemodynamic condition, we performed video-assisted thoracic surgery to remove the hematoma. The bleeding point was in a branch of the ...

background: chlorhexidine (chx) as a gold standard chemical agent appears to be the most effective antimicrobial agent for reduction of both plaque and gingivitis. the aim of this study was to compare the efficacy of two concentrations of digluconate chlorhexidine (chx) solutions (0.12% and 0.20%) on gingival indices and the level of dental staining during 14 days. materials and methods: in thi...