DNA ligases catalyze the repair of phosphate backbone breaks in DNA, acting with highest activity on breaks in one strand of duplex DNA. Some DNA ligases have also been observed to ligate two DNA fragments with short complementary overhangs or blunt-ended termini. In this study, several wild-type DNA ligases (phage T3, T4, and T7 DNA ligases, Paramecium bursaria chlorella virus 1 (PBCV1) DNA li...

Traumatic abdominal wall hernia is a relatively uncommon finding secondary to blunt trauma. We report a unique case of laparoscopic diagnosis and immediate repair of a traumatic anterior abdominal wall hernia after blunt abdominal trauma.

Coronary artery dissection leading to acute myocardial infarction after blunt chest trauma is extremely rare. A 67-year-old woman suffered blunt chest trauma following a traffic accident. The electrocardiogram revealed acute posterior ST-segment elevation and myocardial infarction and coronary angiography demonstrated acute right coronary artery dissection. Following the death of the victim an ...

Small bowel perforation from blunt abdominal trauma is a common injury. Isolated perforation of the small bowel after blunt abdominal trauma is infrequent and the diagnosis can be elusive. A case of isolated perforation from blunt trauma is presented. Deterioration of the clinical picture raised suspicion of acute abdomen, perforated sore. If acute abdomen is the case even with a history of min...

OBJECTIVE To compare the specificity and sensitivity of the skin pathergy test performed with blunt and sharp needles in patients with Behçet's disease. METHODS The skin pathergy test was performed using the simultaneous four needle prick method with blunt and sharp, thick and thin needles in 92 patients with Behçet's disease, 64 healthy controls, and 128 patients without Behçet's disease. Th...

BACKGROUND Blunt thoracic trauma can rarely result in coronary artery injury. Blunt trauma can result in occlusion of any of the coronary arteries or can lead to its rupture and bleeding. Traumatic coronary artery occlusion can lead to myocardial infarction, while its rupture and bleeding can result in hemopericardium and cardiac tamponade, and can be rapidly fatal. Survival after coronary arte...

BACKGROUND During the last century, the management of blunt force trauma to the spleen has changed from observation and expectant management in the early part of the 1900s to mainly operative intervention, to the current practice of selective operative and nonoperative management. These issues were first addressed by the Eastern Association for the Surgery of Trauma (EAST) in the Practice Manag...

purpose: to report a case of hypotonous maculopathy after blunt trauma and its treatment. patient and findings: a 34-year-old woman presented with decreased visual acuity in her left eye following blunt trauma. right eye examination was unremarkable, but visual acuity of left eye was counting fingers. slit lamp biomicroscopy of the left eye was within normal limits, but on funduscopy, papilloma...

introduction lung herniation following blunt chest trauma is extremely rare and only a few hundred cases of this pathology have been reported in the english language medical literature. this type of lung hernia is divided into intercostal, parasternal, or supraclavicular subtypes based on the exact location of the chest wall defect. traumatic intercostal lung hernia is even more uncommon. delay...