Para-aminohippuric acid (PAH) accumulates against a concentration gradient in the ciliary body and independently in the iris of the rhesus monkey eye. This accumulation is inhibited by incubation of 0 degrees C and shows saturation kinetics in both tissues. Cyanide, ouabain, dinitrophenol, iodopyracet, and probenecid effectively depress PAH uptake in both tissues, but anaerobic incubation condi...

Poly(lactic aicd) particles stimulate collagen production through foreign body reaction, contributing to the formation of fibrotic tissues which is beneficial for variety tissue-related therapies such as facial rejuvenation and wound healing.

1. Many previous reports have shown that the ratio of total body potassium to fat-free tissue mass is, on average, higher in men than in women. 2. In an attempt to explain this finding we have re-examined our own data and data taken from the literature. Our own data comprise measurements on 333 healthy people (196 men and 137 women). In all subjects we measured total body potassium and estimate...

Arctic ground squirrels are small mammals that experience physiological extremes during the hibernation season. Body temperature rises from 1°C to 40°C interbout arousal and requires tight thermoregulation maintain rheostasis. Tissues wild-caught were sampled over 9 months assess expression of proteins key thermogenic regulation. Animals sacrificed while aroused, extensor digitorum longus, diap...

Cancer is a complex and diverse group of diseases characterized by the uncontrolled growth spread abnormal cells in body. Tumors, which are commonly associated with cancer, refer to masses tissue that can develop various organs or tissues. arise from almost any cell type body affect different systems. The disease occurs when normal processes division go awry, leading formation malignant tumors....

the present experiment was designed to access the effects of methylmercury chloride ( mehgcl) on antioxidant status, protein concentration, lipid peroxidation and hydroperoxidation in brain parts, spinal cord, lung, heart and pancreas of rats. twenty male wistar rats (3 months old) were divided in saline controls (c) and mehgcl-treated group (mmc). treated rats were intoxicated with mmc at a do...

tissue-engineered biomaterials have existed approximately 40 years as simple biomimetic structures. replacement of human tissue with new tissue can be accomplished by generating replacements outside of the body or in situ in the body. in each case, the key elements are described as the tissue engineering triad of scaffolds, cells, and signals. scaffolds can be produced synthetically or derived ...

the pharmacokinetics of levofloxacin following its single intramuscular administration (3 mg/kg) was investigated in six male buffalo calves. peak plasma level of 2.95 ± 0.13μg/ml was observed at 1 h and the drug level above mic90  in plasma was detected up to 12 h of administration. the bioavailability was 68.1 ± 5.4% and levofloxacin was bound to the plasma proteins to the extent of 19.1 ± 1....