a 42-year-old male with history of hcv, presented with cutaneous lesions which were initiated from 2 weeks ago. lesions presented with tenderness and red bulla in anterior aspect of left leg. the lesion gradually began to rupture and desquamation. patient had similar lesions during the last year. hyperpigmentation in old lesions was seen. porphyria cutanea tarda was suspected. diagnosis was con...

Background and aim: Adult T cell leukemia/lymphoma (ATLL) is an aggresive malignancy which may occur in human T lymphotropic virus1(HTLV1) infected persons. HTLV1 is endemic in Khorasan with prevalence of 2.3% in general population. Since specific cutaneous manifestations of lymphoma may occur in a significant number of patients, we studied ATLL patients in Mashhad.Mate...

background: oral white and red lesions are usually assumed as premalignant lesions. epidemiological characteristics of these lesions seem to be important. the aim of this study was to determine the prevalence of the oral red and white lesions in patients referred to oral and maxillofacial pathology department in isfahan school of dentistry during last two decades. methods: in this descriptive s...

Adrenal lesions are commonly observed during 18F-FDG PET/CT studies. Although, most of these lesions are considered benign, an important consideration in oncologic patients is metastasis. Benign lesions, such as adenomas usually present with low 18F-FDG uptake, although overlap with malignant lesions exist and clear SUV cut-off for distinguishing adrenal adenomas has not b...

the clinical and phenotypic features of two siblings (a 12 years old girl and her 7 year old brother) with cockayne syndrome are described. the main problems were mild to moderate mental retardation, dwarfism, clumsy gait, photosensitive skin lesions and progeroid (senile like) appearance. brain ct - scans revealed symmetrical, well defined areas of calcification mainly located at lenticular nu...

t his paper presents a new feature selection approach for automatically extracting   ms lesions in 3d mr images. presented method is applicable to different types of ms lesions. in this method, t1, t2 and flair images are firstly preprocessed. in the next phase, effective features to extract ms lesions are selected by using a genetic algorithm. the fitness function of the genetic algorithm is t...

Objective: Measurement of blood-brain permeability dysfunction in active and chronic MS lesions with T1-weighted dynamic contrast-enhanced MRI to show variation in inflammatory activity Background: blood-brain-barrier perfusion characterization impaired in MS as some studies have shown recently buta comparison between perfusion parameters in contrast-enhanced and non-enhanced lesions not have ...

Among oral lesions, we encounter a series of malignant epithelial lesions that go through clinical and histopathologic processes in order to be diagnosed. Identifying these processes along with the etiology knowledge of these lesions is very important in prevention and early treatments. Dysplasia is the step preceding the formation of squamous cell carcinoma in lesions which have the potential ...