Background: Acute myeloid leukemia (AML) is characterized by the proliferation of myeloid precursors and abnormal differentiation of hematopoietic stem cells, which results in the accumulation of immature cells in the bone marrow (BM). The accumulation of these cells in the bone marrow causes molecular and cellular changes in the microenvironment of the bone marrow. The adiponectin hormone orig...

sulphur mustard (sm) is an alkylating agent that was first used as a chemical warfare agent during the first world war in 1917. sm is readily absorbed from the skin, respiratory and gastrointestinal tract and is distributed to several organs. sm may act rapidly and persistently upon dna replicating mechanism of the individual cells during mitosis particularly in the hematopoietic system. of 233...

changes (bmd) and osteoporosis .helico bacter pylori which is a known cause of gastritis and peptic ulcer osteopprosis is one major cause of bone fracture and subsequent morbidity and mortality in the elderly population. several clinical and demographic parameters including aging, menopause, parity , inflammatory disease, hormonal, gastrointestinal, renal and metabolic disorders like vitamin d ...

background: fluoride (f−) is a trace element that is incorporated into bone mineral during bone formation. this study assessed the effect of increasing fluoride doses on the bone formation and microarchitecture on the femur of rats by histological, and histometrical methods. materials and methods: a total of 16 rats was divided into one group of control and three groups of animals that received...

Bone turnover markers (BTM) are gaining ground in clinical practice but to fully use their potential there is a need for establishing valid reference intervals (RI). Consequently, the purpose of study was establish general RI as well suggested carboxy-terminal cross-linked telopeptide type I collagen (?-CTX), pro-collagen N-terminal propeptide (PINP), osteocalcin (OC) and bone-specific alkaline...

Animals with anterior or posterior neocortical lesions as well as intact control animals were evaluated for changes in a-adrenergic sensitivity at five postoperative times. Colonic temperature decreases were measured in response to clonidine at each of the postoperative periods. The result indicated that a heightened heat-loss response was induced by clonidine that lasted 21 or more days after ...

There has recently been a great deal of interest in cognitive interventions, particularly when applied in older adults with the goal of slowing or reversing age-related cognitive decline. Although seldom directly investigated, one of the fundamental questions concerning interventions is whether the intervention alters the rate of cognitive change, or affects the level of certain cognitive measu...

This study examines 5 types of personality continuity--structural, mean-level, individual-level, differential, and ipsative--in a representative population (N=498) and a twin and sibling sample (N=548) of children and adolescents. Parents described their children on 2 successive occasions with a 36-month interval using the Hierarchical Personality Inventory for Children (I. Mervielde & F. De Fr...

Personality-relationship transactions were investigated in a general population sample of young German adults with three assessments over 8 years. Four general findings were obtained. First, personality development was characterized by substantive individual differences in change. Second, bivariate latent growth models indicated that individual differences in personality change were substantial...

conclusion dt-sfp can improve the detection of relatively early bone abnormalities in acetabular and proximal femur compared with conventional radiography. dt-sfp can also observe the abnormal impact between acetabular and proximal femur. patients and methods ninety-four consecutive patients with discomfort around the hip joint underwent dt-sfp and conventional radiography. the imaging features...