Recent findings suggest that contact stress is a potent predictor of subsequent symptomatic osteoarthritis development in the knee. However, much larger numbers of knees (likely on the order of hundreds, if not thousands) need to be reliably analyzed to achieve the statistical power necessary to clarify this relationship. This study assessed the reliability of new semiautomated computational me...

A three-dimensional model of interstitial fluid flow and passive species transport within mineralized regions surrounding cross-cortical vessel canals is developed. In contrast to earlier studies, the present model applies to circulatory, non-stress-induced interstitial flow in porous cortical bone. Based on previous experimental observations, the canals are modeled as line sources that pass at...

Allergic contact hypersensitivity to metals is a delayed-type allergy. Although various metals are able to induce an allergic reaction, nickel is the most frequent cause of metal allergy worldwide. The high prevalence of skin sensitization to that metal is the result of an ubiquitous exposure, being contained in different everyday things, such as detergents, cheap jewelry, cosmetics, coins, but...

Bone fracture due to an accident, aging or diseases is a feature of everyday life. One of the principal methods of repair and reconstruction of such a fracture is based on drilling the bone and fixing its separate parts together using screws, wires and plates. Morphology of the drilled hole surface and fixative components such as screws, pins and hooks influences strength of the bonds between t...

In this study, the Bioeutectic® blocks were inserted into the critical size defects of eight rabbits, using both tibiae, and the physical and chemical nature of the remodeled interface between the Bioeutectic® implants and the surrounding bone were performed at four and 15 months. The results showed a new fully mineralized bone growing in direct contact with the implants. The ionic exchange, ta...

PURPOSE The purpose of this study was to characterize the osseointegration of the fibronectin-coated implant surface. METHODS Sand-blasted, large-grit, acid-etched (SLA) surface implants, with or without a thin calcium phosphate and fibronectin coating, were placed in edentulous mandibles of dogs 8 weeks after extraction. All dogs were sacrificed forhistological and histomorphometric evaluati...

PURPOSE The purpose of this study was to confirm the validity of laser treated implant surfaces, with regard to high superficial purity preservation and to extremely regular and uniform roughness surfaces. METHODS In this in vivo study, seven different laser treated implant surfaces were analyzed. A diode-pumped solid state source laser, in a Q-Switch output mode, was used at various waveleng...

PURPOSE To test the mechanical stability and histologic osseointegration under load-bearing conditions of 2 different materials, pyrocarbon (Py) and titanium (Ti), in a rabbit model. METHODS Proximal interphalangeal implants (9 Ti, 8 Py) were placed into rabbit knees and the animals were killed after 3 months. Subsidence was assessed by monthly x-rays. Mechanical stability was measured with a...

This study evaluated bone response to a Ca- and P- enriched titanium (Ti) surface treated by a multiphase anodic spark deposition coating (BSP-AK). Two mongrel dogs received bilateral implantation of 3 Ti cylinders (4.1 x 12 mm) in the humerus, being either BSP-AK treated or untreated (machined - control). At 8 weeks postimplantation, bone fragments containing the implants were harvested and pr...

In this research, the removal of Reactive Red 198 dye (RR-198) by Cuttlefish bone powder was investigated. The adsorbent was prepared in laboratory conditions and ground by ASTM standard sieves (60-100 mesh). The progress of the process is monitored spectrophotometrically by measuring the absorbance of dye at 518 nm wavelength. In addition, the effects of process parameter...