Mastocytosis is a rare, heterogeneous disease of complex etiology, characterized by a marked increase in mast cell density in the skin, bone marrow, liver, spleen, gastrointestinal mucosa and lymph nodes. The most frequent site of organ involvement is the skin. Cutaneous lesions include urticaria pigmentosa, mastocytoma, diffuse and erythematous cutaneous mastocytosis, and telangiectasia macula...

Bone complications occur frequently in Gaucher disease (GD) and reduce the quality of life of these patients. Skeletal involvement is an important indication for treatment to ameliorate symptoms and reduce the risk of irreversible and debilitating disease. Bone biomarkers have been used to assess disease status and the response to therapy in a number of bone disorders. Here, we examine the lite...

introduction: almost all malignant tumors have the potential to eventually produce bone metastasis. the aim of the current study was to report the distribution pattern and imaging characteristics of bone metastases detected by conventional whole body bone scintigraphy in patients with different types of malignancies and to assess their relationship with the complaint of bone pain. methods: as ...

hydatid disease is a rare parasitic disease, which mainly involves liver then lung tissues. cardiac involvement is very rare, especially when there is not hepatic involvement. we describe a 47-year-old woman with a history of a lung hydatid cyst who was referred to rajaei heart center, tehran, iran in 2012. her chest computed tomographic scan showed a cardiac mass. echocardiographic examination...

Received March 29, 2003 Abstract Congenital infantile myofibromatosis is a rare disorder with multiple fibromatous tumours in skin, bone, muscle, viscera and subcutaneous tissue presenting in early infancy. Multiple lytic bone lesions and vertebra involvement are also common, mimicking the clinical picture of metastatic tumours. However, it is a disease with variable prognosis depending on the ...

Hepatocellular carcinoma (HCC) is relatively common worldwide. Until a few years ago skeletal involvement from HCC was rarely diagnosed. Thanks to novel imaging techniques and multidisciplinary treatment approaches, the overall survival in HCC patients has prolonged, and bone involvement has significantly increased currently. This short review summaries the value of bone scintigraphy in patient...

Solitary metastasis of uveal melanoma to bone is extremely rare and usually associated with other organ involvement. We present a rare case of an ocular melanoma patient presenting with solitary metastasis to the clavicle two years after enucleation, without any other organ involvement. In this report, we tried to present our treatment strategy for the solitary metastasis of bone.