Studies of the epidemiology of osteoporosis and of drug treatments for it have challenged the concept that denser bone means stronger bone. Bone strength or resistance to fracture is not easily measured by routine densitometry, being a function of both density and quality.

Introduction: The low regeneration of bone in defective bones causes therapeutic problems. Various strategies to assess the healing of bone defects have been used which they include histological and histo-chemical analysis in an invasive study. The purpose of this study was to determine the ultrasonic parameters of bone as a promising noninvasive technology for assessing bone repair process. Ma...

Greater understanding and acceptance of the new concept "bone quality", which was proposed by the National Institutes of Health and is based on bone cells and collagen fibers, are required. The novel protein Semaphorin3A (Sema3A) is associated with osteoprotection by regulating bone cells. The aims of this study were to investigate the effects of mechanical loads on Sema3A production and bone q...

PURPOSE Bone drilling is a major part of orthopaedic surgery performed during the internal fixation of fractured bones. At present, information related to drilling force, drilling torque, rate of drill-bit penetration and drill-bit rotational speed is not available to orthopaedic surgeons, clinicians and researchers as bone drilling is performed manually. METHODS This study demonstrates that ...

Background: The purpose of this retrospective study was to analyze the long-term results of revision ORIF, jointcontracture release, and autogenous bone-grafting in the treatment of distal humerus frac-ture nonunions in older agedpatients with poor bone quality or bone loss who would have been candidates for total elbow arthroplasty.Methods: Seven patients (average age at inde...

Limited opportunity for movement and load-bearing exercise for conventionally caged laying hens leads to bone loss and increased susceptibility to osteoporosis, bone fractures, and cage layer fatigue, all of which compromise hen welfare and have negative consequences for production. The objective of this study was to compare bone mineral density (BMD) and strength measures of White Leghorns hou...

Introduction: Numerous factors are considered to determine human bone quality. Particularly, volumetrically evaluated bone mineral density (DXABMD) as well as the mechanical properties of bone samples serve to assess fracture risks. However, the differentiation and degree of mineral content and/or morphology effects on bone toughness remained to a large extent unanswered due to large measuring ...