OBJECTIVES The aim of the present study was to compare a newly developed biodegradable polylactide/polyglycolide/N-methyl-2-pyrrolidone (PLGA/NMP) membrane with a standard resorbable collagen membrane (RCM) in combination with and without the use of a bone substitute material (deproteinized bovine bone mineral [DBBM]) looking at the proposed tenting effect and bone regeneration. MATERIALS AND...

Arthritis is a multifactorial process involving the joint articular surfaces, synovial fluid, supporting ligaments and musculature, anatomic alignment, and subchondral bone and bone marrow. Recent literature has shown a safe and efficacious procedure of symptomatic bone marrow lesions in the knee with an injectable calcium phosphate bone substitute, known as Subchondroplasty (SCP). The authors ...

Displaced intra-articular calcaneal fractures Sanders 3 and 4 leaving a large bone void after reposition, continue to pose a therapeutic challenge. The purpose of this study was to determine the effects of open reduction and internal fixation (ORIF) combined with the injectable bone substitute CERAMENTTM|BONE VOID FILLER in patients with a bone gap > 2 cm after reduction. Twelve consecutive cas...

Objective- To determine the effect of selected bone graft on the compression properties of radialbone in rabbit.Design- Experimental in vivo study.Animals- A total of 45 adult male New Zealand white rabbits.Procedures- The rabbits were anesthetized and a one-cm-full thickness piece of radial bone wasremoved using oscillating saw in the all rabbit. The rabbits were divided into 5 groups on theba...

BACKGROUND/AIMS The aim of this study was to generate an axially vascularized bone substitute. The arteriovenous (AV)-loop approach in a large-animal model was applied in order to induce axial vascularization in a clinically approved processed bovine cancellous bone (PBCB) matrix of significant volume with primary mechanical stability and to assess the course of increasing axial vascularization...

STUDY DESIGN A retrospective study. PURPOSE To compare the clinical and radiological outcomes of autogenous bone graft and cage with bone substitute for anterior cervical discectomy and fusion. OVERVIEW OF LITERATURE The clinical outcomes of cage with bone substitute for anterior cervical discectomy and fusion is satisfactory. METHODS Eighty four patients who underwent cervical spine surg...

The application of porous bio-nanocomposites polymer has greatly increased in the treatment of boneabnormalities and bone fracture. Therefore, predicting the mechanical properties of these bio-nanocompositesare very important prior to their fabrication. Investigation of mechanical properties like (elasticmodulus and hardness) is very costly and time-consuming in experimental t...