PURPOSE To report the development of optic neuropathy after botulinum A toxin injection for restrictive myopathy from thyroid-related orbitopathy (TRO). METHODS We retrospectively reviewed the records of three patients with TRO who underwent botulinum A toxin injection for restrictive myopathy and subsequently developed optic neuropathy. Development of optic neuropathy was measured by visual ...

background :â  obesity is a tremendous, increasing health problem worldwide. there are multiple endoscopic treatments for obesity. this study is a systematic review of researches on these methods and an evaluation of their safety and efficacy. materials and methods : we conducted a medline electronic research to review relevant english articles and abstracts published in the previous ten years(...

background: patients with gastroesophageal reflux disease (gerd) unresponsive to proton pump inhibitor (ppi) therapy are often labeled as having refractory gerd. one of the probable etiologies of refractory gerd is delayed gastric emptying. refractory gerd associated with gastroparesis is a complex condition with no definitive treatment to date. we opted, for the first time, to test the hypothe...

Background: Severe axillary hyperhidrosis causes considerable emotional stress to individuals affected with this condition. Existing topical and surgical therapies are either ineffective or associated with unacceptable morbidity and sequelae. Objective: In this study we attempted to determine the effect of botulinum toxin A (Dysport) in the treatment of axillary hyperhidrosis. Patients and Meth...

The action of tetanus toxin on the motor system in experimental tetanus relating to the clinical one was reviewed. Special attention was paid to several controversial results in recent years.

The chemical forms of Clostridium botulinum 62A and 213B were prepared, and their heat resistances were determined in several heating media, including some low-acid foods. The heat resistance of C. botulinum spores can be manipulated up and down by changing chemical forms between the resistant calcium form and the sensitive hydrogen form. The resistant chemical form of type B spores has about t...

4-Aminopyridine and 3,4-diaminopyridine were evaluated for their abilities to delay the onset of paralysis due to botulinum neurotoxin types A, B, and E. Experiments were done on phrenic nerve-hemidiaphragm preparations excised from mice. At a concentration that produced an enhancement in muscle twitch amplitude, 4-aminopyridine and 3,4-diaminopyridine delayed the onset of paralysis due to botu...

Background and aim: Appearance concerns are increasingly common. Indeed, clinical surveys in the private settings show that more and more people are dissatisfied with some aspects of their physical appearance. Concurrently, there is increasing demand for cosmetic specialists to perform procedures to enhance physical appearance. It is hypothetized that body image and acceptance of cosmetic surge...

Botulinum toxin has been used for the treatment of many clinical disorders by producing temporary skeletal muscle relaxation. In pain management, botulinum toxin has demonstrated an analgesic effect by reducing muscular hyperactivity, but recent studies suggest this neurotoxin could have direct analgesic mechanisms different from its neuromuscular actions. At the moment, botulinum toxin is wide...

The key points to remember about abobotulinumtoxinA are as follows: BoNTA-ABO (abobotulinumtoxinA [Dysport]; Medicis Aesthetics, Scottsdale, AZ) and BoNTA-ONA (onabotulinumtoxin A [Botox Cosmetic]; Allergan, Irvine, CA) are both derivatives of botulinum toxin A produced from different strains of the bacterium Clostridium botulinum through proprietary manufacturing processes, and both are approv...