This study investigated the biochemical effects of administration of three types of recombinant growth hormone (GH; somatotropin) to the Thoroughbred horse. Equine or bovine or porcine GH was administered at a recommended dosage to 3-5-year old Thoroughbred geldings, for up to 21 days. It was shown that, in addition to equine GH, bovine and porcine GH were active in the horse; however, porcine ...

The discussion of effects of recombinant bovine somatotropin (rbST) administration on the metabolism of lactating dairy cows presented is divided into two parts: short term and long term. Short-term effects are evident during the initial period of treatment when milk production is increased but feed intake has not yet increased. During this period body reserves are mobilized to support the high...

Impressive progress has been made during the past 15 years in our understanding of the biology of somatotropin (ST) in domestic animals. In part, this progress was sparked by advances in biotechnology that made feasible the production of large quantities of recombinant bovine ST (bST) and porcine ST (pST). The availability of recombinant bST and pST resulted in an exponential increase in invest...