We used postembedding electron microscopic immunocytochemistry with colloidal gold to determine the ultrastructural distribution of Na+,K(+)-ATPase in the sciatic and optic nerves of the rat. Using a polyclonal antiserum raised against the denatured catalytic subunit of brain Na+,K(+)-ATPase, we found immunoreactivity along the internodal axolemma of myelinated fibers in both nerves. This antis...

Introduction: Multiple sclerosis (MS) is a chronic, autoimmune, and inflammatory nervous system disease. It leads to the loss of myelin in the white matter of brain, spinal cord and optic nerves. As a chronic disease with sudden and unpredictable Side effects and complications of the disease will lead to disability and dependency in life. Causes neurologic symptoms and sig. The purpose of the p...

Abnormalities of ocular motility serve as valuable signposts for the localization of lesions of the cerebral hemispheres, brainstem, cranial nerves, and even striated muscle. Ocular symptoms and signs are particularly helpful when examining the patient in coma (see Chapter 22). In this chapter, the term ocular motor refers to cranial nerves III (oculomotor), IV (trochlear), and VI (abducens), c...

BACKGROUND AND PURPOSE The abducent nerve is difficult to identify reliably and consistently with conventional radiologic techniques. In this study, a 3D fast asymmetrical spin-echo MR imaging technique was used to obtain detailed images of the abducent nerve in normal volunteers. METHODS The 3D fast asymmetrical spin-echo MR protocol was used to image the abducent nerves in 24 normal volunte...