introduction: bone metastases are the most common cause of cancer-related pain in various primary malignant tumors, most often, breast and prostate. 188re-hydroxyethylidene diphosphonate (188re-hedp) is a new and less expensive bone seeking radiopharmaceutical with favorable physical characteristics of the radionuclide such as short half life of 16.9h, maximal β energy of 2.1 mev with a 15% γ-c...

BACKGROUND Persistent pain after breast cancer surgery affects up to 60% of patients. Early identification of those at higher risk could help inform optimal management. We conducted a systematic review and meta-analysis of observational studies to explore factors associated with persistent pain among women who have undergone surgery for breast cancer. METHODS We searched the MEDLINE, Embase, ...

BACKGROUND The efficacy of local anesthetic wound infiltration for the treatment of acute and chronic postoperative pain is controversial and there are no detailed studies. The primary objective of this study was to evaluate the influence of ropivacaine wound infiltration on chronic pain after breast surgery. METHODS In this prospective, randomized, double-blind, parallel-group, placebo-contr...

BACKGROUND Patients undergoing mastectomy and prosthetic breast reconstruction have significant acute postsurgical pain, routinely mandating inpatient hospitalization. Liposomal bupivacaine (LB) (Exparel; Pacira Pharmaceuticals, Inc., Parsippany, N.J.) has been shown to be a safe and effective pain reliever in the immediate postoperative period and may be advantageous for use in mastectomy and ...

PURPOSE Persistent pain is a common side effect of breast cancer treatment. The present study aimed to assess the prevalence, associated treatment-related factors, and the type of pain (neuropathic or nociceptive) in patients who had undergone a unilateral mastectomy. METHODS All women who underwent a unilateral mastectomy at a University Hospital between 2009 and 2013 were eligible for inclu...

OBJECTIVE The purposes of this study were to determine the coexistence of mastalgia and fibromyalgia, to investigate the effects of this combination on pain patterns, and to discuss the status of breast pain in the diagnostic algorithm of fibromyalgia syndrome. METHODS Sixty-one female patients reporting breast pain during the last three months and 53 female patients diagnosed with fibromyalg...

After adjuvant therapies, the 5-year survival of breast cancer patients with localized and locoregional breast cancer is estimated to be 98% and 83% respectively 1. Because many patients become longterm survivors, concerns about the mediumand long-term consequences of their treatment regimens have led to multiple quality-of-life (qol) studies that have demonstrated significant emotional, cognit...

background: breast implant associated anaplastic large t- cell lymphoma is a rare type of non-hodgkin lymphoma, with a reported incidence of 0.3% per 100,000 women with breast prosthesis per year. it presents most commonly as a peri-implant seroma, but may also present as a capsular mass, tumor erosion through skin, in a regional lymph node, or found incidentally during revision surgery. case p...