Cacao is a plant that belongs to the Malvaceae family. The n-hexane extract of cocoa pod husks (Theobroma cacao L) and its fraction was determined for cytotoxic activity by Brine Shrimp Lethality Test (BSLT) method which showed very strong activity. Isolation chemical components from Theobroma L. 7.4 (TCH 7.4) TCH 9.1 subfraction obtained with LC50 value 20.39 ppm 5.52 ppm, respectively. compou...

Medicinal plants are a good source of therapeutic drugs because they contain phytochemical compounds. Cat's whiskers (Orthosiphon stamineus) and miana (Coleus artropurpureus) that widely used as herbal medicines. However, there no studies related to toxicology ensure its safety. The aim this study was determine the toxicity 96% ethanol extract cat leaves shrimp (Artemia salina Leach) larvae. To...

Previous studies indicate that the hatching success of brine shrimp (Artemia franciscana) cysts is surprisingly sensitive to ambient metal concentrations. These studies estimated median effective concentrations (EC50s) of 7, 5, and 28 microg l-1 for Cd, Cu, and Zn, suggesting that the hatching end point for A. franciscana is the most sensitive tested to date for Cd and Zn in saline environments...

Sterculia quinqueloba (Garcke) K. Schum and Canthium crassum Hiern extracts were evaluated for antimicrobial activity using 96-well-microtitre serial micro-dilution method against Vibrio cholera, Klebsiella oxytoca, Klebsiella pneumonia, Streptococcus pyogenes, Staphylococcus aureus and Candida albicans. All extracts exhibited antimicrobial activity with minimum inhibition concentration range o...

The goal of the present work is to fabricate selenium nanoparticles utilising Morinda citrifolia leaves extract via green approach. UV-Vis spectroscopy, FT-IR, and TEM were used characterise nanoparticles. size generated SeNPs in was anticipated be 12-160 nm based on images. antioxidant activity NPs discovered 66.7 83.7% free radical inhibtion. When concentration rises, viability cancer cells d...

A follow-up chemical investigation to methanol extract of Conyza dioscoridis (Family Asteraceae) led to the isolation of seven compounds (1-7). The isolated compounds identified as 2-(3,4-dihydroxyphenyl)ethyl-2-O-[6-deoxy-α-Lmannopyranosyl-4-(3,4-dihydroxyphenyl)-2-propenoate]-β-D-glucopyranoside (1), rutin (2), isoquercetin (3), E-caffeic acid (4), gallic acid (5), quercetin (6), β-Sitosterol...

We evaluated the antibacterial activity and cytotoxicity of endophytes isolated from Scapania verrucosa Heeg., which belongs to the liverwort class. A total of 49 endophytic fungi were isolated from S. verrucosa and classified into seven genera and one family in our previous study. In this study, the cytotoxic activity of the endophytes was assessed using the brine shrimp lethality bioassay, se...

PURPOSE This study was aimed to evaluate general toxicity, anti-oxidant activity and effects of Ficus carica leaves extract on ischemia/reperfusion injuries. METHODS Antioxidant activity, total phenolic and flavonoid compounds of 70% methanolic extract of Ficus carica leaves were measured. The general toxicity test was carried out by brine shrimp lethality assay. Isolated hearts of male rats ...