Codeine (methyl morphine) is a widely used opioid that is administered alone or in combination with other drugs, such as antihistamines, decongestants, and mild analgesics. There are few reports of generalized dermatitis induced by oral codeine and cross-reactivity with morphine [1-4]. A 43-year-old man experienced 3 episodes of generalized pruriginous rash after taking analgesic and antitussiv...

BACKGROUND Bronchiectasis is a chronic respiratory disease characterised by abnormal dilatation of the bronchi, and presents typically with a chronic productive cough (or chronic wet cough in children) and recurrent infective exacerbations. It significantly impacts daily activities and quality of life, and can lead to recurrent hospitalisations, severe lung function impairment, respiratory fail...

drug administration. However, the barrier properties of the outermost layer, the stratum corneum, have limited the number of successful transdermal dosage forms developed thus far. One of the strategies for overcoming this problem is temporary local reduction of the barrier function of the stratum corneum with the aid of a percutaneous absorption enhancer. Sucrose fatty acid esters (sugar ester...

Successful Expression of Adenovirus E3 CR1 Genes from constructs carrying Adenovirus Tripartite Leader sequences: a technical breakthrough Camden Bair, Poornima Kotha, and Adriana Kajon Over 70 human adenovirus genotypes have been described to date and classified into seven species (HAdV-A to -G). One of the few characteristics distinguishing HAdV genomes of different species is the unique repe...