Assessing Brucella ceti Infections in Oregon and Washington Dolphins that Stranded with Histopathological Lesions Resembling Neurobrucellosis, 2006-2014 Tabitha George This thesis documents the presence of Brucella ceti in the Pacific white-sided dolphin (Lagenorhynchus obliquidens), striped dolphins (Stenella coeruleoalba), and shortbeaked common dolphins (Delphinus delphis) that stranded with...

Previous findings indicate that Brucella antigens and those from nonpathogenic alphaproteobacteria (NPAP) are cross-recognized by the immune system. We hypothesized that immunization with NPAP would protect mice from Brucella infection. Mice were immunized subcutaneously with heat-killed Ochrobactrum anthropi, Sinorhizobium meliloti, Mesorhizobium loti, Agrobacterium tumefaciens, or Brucella me...

In this study, a localized surface plasmon resonance (LSPR) nanobiosensor was designed to quantify anti-Brucella antibodies in the human sera. Smooth Lipopolysaccharide (LPS) extracted from Brucella melitensis via modified hot phenol water method and fixed on of gold nanoparticles by covalent interactions with functionalized nanoparticles. To obtain best performance probe, ratio LPS nanoparticl...

Brucella spp. are facultative intracellular parasitic pathogens that can survive and multiply in professional and nonprofessional phagocytes. These pathogens are responsible for brucellosis, which can cause abortion in domestic animals and undulant fever in humans. Brucella spp. can survive in a variety of cells and their virulence and chronic infections are thought to be due to their ability t...

Pathogenic brucellae are the agent of brucellosis, a disease that causes abortion and infertility in natural hosts such as sheep, goats, or cattle. Brucella melitensis, Brucella abortus, and Brucella suis are the most pathogenic Brucella species for humans and also the most relevant bacteria involved in economical loses and in animal and human health problems. In addition, these Brucella repres...

background pyogenic bacteria and especially staphylococcus aurous (s. aurous) are the most common cause of chronic osteomyelitis. not only treatment protocol of chronic osteomyelitis occasionally is amiss but also this malady responds to treatment difficultly. objectives this study investigates antibiotic resistance pattern of s. aurous isolated from iranian patients who suffer from chronic ost...

  Background: Tuberculosis is an essential problem for healthcare systems especially in developing countries . All newborns are given Bacillus Calmette-Guérin (BCG) vaccine in Iran which is prepared from live bovine tuberculosis bacillus, and is given to protect against tuberculosis. Osteomyelitis secondary to BCG vaccination is rare and usually involves epiphysis of long tubular bones. Methods...

The letter of Yang et al. (1) is an interesting account of the continuing issues associated with the misidentification of Brucella species by the current commercial identification systems. As mentioned in the letter, we experienced similar issues with the commercial bacterial identification assays that rely on phenotypic laboratory tests (2). These systems remain unreliable for identification o...

Monoclonal antibodies which bind Brucella A lipopolysaccharide (LPS)-specific, M LPS-specific, or cross-reactive epitopes were used as reagents in quantitative dot blot, Western blot (immunoblot), and immunoprecipitation analysis of Brucella whole cells, whole-cell extracts, and purified LPS preparations. This set of monoclonal antibodies detected four unique epitopes on Brucella LPS. The speci...

Older adults are predisposed to osteomyelitis either because of an increased incidence of associated disorders (e.g., peripheral vascular disease, diabetes mellitus, malnutrition and poor dentition) or because of surgical procedures that are frequently performed in the elderly population (e.g., dental extractions, open-heart surgery, and prosthetic joint replacement or osteosynthesis). Two type...