background: fetal growth in diabetic pregnancies is a complex process and probably abnormalities in other metabolic pathways such as protein and lipid, as well as carbohydrate are responsible for delivering of macrosomic newborn. objective: the purpose of this study was to investigate the association between fetal growth and different maternal metabolic parameters in women with gestational diab...

Plasma-derived lipid transfer protein (LTP) facilitates the transfer of cholesteryl ester and triglyceride between all lipoproteins. Kinetic models of the transfer event have suggested that transfer is facilitated through the physical interaction (binding) of LTP with its lipoprotein substrate. Such binding has been observed previously between LTP and high density lipoprotein (HDL), but not bet...

Lipoproteins are large lipid/protein complexes that play a major role in transport of lipids and lipophilic molecules in the plasma and central nervous system (CNS). Plasma lipoproteins represent a dynamic continuum of particles that are constantly undergoing remodulation in their lipid and protein components leading to re-structuring of the particle under normal physiological conditions. The r...

Bacterial lipoproteins are lipid-anchored proteins that contain acyl groups covalently attached to the N-terminal cysteine residue of the mature protein. Lipoproteins are synthesized in precursor form with an N-terminal signal sequence (SS) that targets translocation across the cytoplasmic or inner membrane (IM). Lipid modification and SS processing take place at the periplasmic face of the IM....

BACKGROUND Low-density lipoproteins (LDL) have been identified as the major atherogenic lipoproteins and have long been identified by the National Cholesterol Education Project (NCEP) as the primary target of cholesterollowering therapy. LDL particles consist of a surface coat composed of phospholipids, free cholesterol, and apolipoproteins, surrounding an inner lipid core composed of cholester...

c Holding Company for Biological products and Vaccines (VACSERA-Egypt). Background: Apolipoprotein B (ApoB) is the major protein component of chylomicrons, low-density lipoproteins (LDL), very low density lipoproteins (VLDL) and intermediate-density lipoproteins (IDL) and is the ligand for the LDL receptor. ApoB plays an important role in the maintenance of cholesterol homeostasis and lipoprote...

A column chromatographic procedure utilizing Silica Gel C is described for separating lipid components of serum and lipoproteins into individual fractions containing hydrocarbons (I), cholesterol esters (II), triglycerides (111), cholesterol (IV) , free fatty acids (V) , and phospholipids (VI). Silica Gel G required no pretreatment except adjustment of moisture content to 10%. The method afford...

Journal: Biochemistry and Cell Biology Manuscript ID bcb-2015-0154.R1 Manuscript Type: Invited Review Date Submitted by the Author: 19-Jan-2016 Complete List of Authors: Maxfield, Frederick; Weill Cornell Medical College, Biochemistry Iaea, David; Weill Cornell Medical College, Pipalia, Nina; Weill Cornell Medical College, Biochemistry Keyword: Cholesterol, STARD4, lipoproteins, Niemann-Pick C,...

Preprolipopoprotein diacylglyceryl transferase (Lgt) is the gating enzyme of lipoprotein biosynthesis, and it attaches a lipid structure to the N-terminal part of preprolipoproteins. Using Lgt from Escherichia coli in a BLASTp search, we identified the corresponding Lgt homologue in Mycobacterium tuberculosis and two homologous (MSMEG_3222 and MSMEG_5408) Lgt in Mycobacterium smegmatis. M. tube...

Patients with hemorrhagic fever with renal syndrome (HFRS) often exhibit altered serum lipid and lipoprotein profile during the oliguric phase of the disease. Serum lipid and lipoprotein profiles were assessed during the oliguric and recovery phases in six male patients with HFRS. In the oliguric phase of HFRS, the apolipoprotein (apo) C-III content in high-density lipoproteins (HDL) was elevat...