Glioblastomas (GBM) are associated with high rates of relapse. These brain tumors are often resistant to chemotherapies like temozolomide (TMZ) and there are very few treatment options available to patients. We recently reported that polo-like kinase-1 (PLK1) is associated with the proliferative subtype of GBM; which has the worst prognosis. In this study, we addressed the potential of repurpos...

In order to develop original and efficient visible light response photocatalysts for degrading organic pollutants in wastewater, new photocatalysts Bi₂GaSbO₇ and Bi₂InSbO₇ were firstly synthesized by a solid-state reaction method and their chemical, physical and structural properties were characterized. Bi₂GaSbO₇ and Bi₂InSbO₇ were crystallized with a pyrochlore-type structure and the lattice p...

the advancement of information and communications technologies (ict) has significantly intensified market competition the world over. one of the most widespread solutions is the use of enterprise resource planning systems that has proved to support the integration and automation of the processes, the improvement of the performance, and the reduction of costs. erp involves the planning and manag...

In this paper, we introduce a new sort of interval valued $left(in ,in vee q_{widetilde{k}}^{widetilde{delta }}right) $-fuzzy bi-ideal in ordered semigroups which is the generalization of interval valued $left( in ,in vee q_{%widetilde{k}}right) $-fuzzy bi-ideal and interval valued $left( in ,in vee qright) $-fuzzy bi-ideal of ordered semigroups. We give examples in which we show that these str...

Effective Business Intelligence (BI) is essential for companies in today’s business environment. The benefits from the adoption and use of BI vary from company to company. It has been suggested that the level of BI success is associated with a company’s level of BI experience or maturity. Researchers have attempted to map the various BI practices to BI Maturity Models. This paper investigates t...

Many organizations have recognized the importance of increasing commitment towards delivering longterm success of Business Intelligence (BI). However, effective BI strategies and governance to accommodate the rapid growth of data volumes are still scarce. Furthermore, there appears to be low usage rates of BI and analytics among business users. Consequently, many organizations are still positio...

Bee venom is a rich source of pharmacologically active substances. In this study, we identified a bumblebee (Bombus ignitus) venom Kunitz-type serine protease inhibitor (Bi-KTI) that acts as a plasmin inhibitor. Bi-KTI showed no detectable inhibitory effect on factor Xa, thrombin, or tissue plasminogen activator. In contrast, Bi-KTI strongly inhibited plasmin, indicating that it acts as an anti...

For a classical two-dimensional one-component plasma (with a logarithmic interaction), the onebody density can be calculated exactly when the coupling constant has the special value 0393 = 2. The behaviour of this density is studied near the wall of the circular box which encloses the system. If there is an excess charge, it concentrates near the wall. The density at the wall is related to the ...