background : gastric cancer is a common and lethal disease throughout the world. in iran with 7300 new cases annually, it is the first cause of cancer related death in both sexes. regarding the high incidence (10.5/100000 individuals) of gastric can­cer and priority of prevalence index in cancer management, in this study we tried to determine 1, 2-3 and 4-5 year point preva­lence of the disease...

background: northeast iran has one of the highest rates of esophageal cancer in the world which is mainly squamous cell carcinoma (e scc). celiac disease (cd) has been identified as a risk factor for escc. the aim of this study is to determine the prevalence of cd in gonbad at northeast iran and probable relation between celiac and escc. materials and methods: fourteen hundred inhabitants of no...

background: stomach cancer has the highest prevalence of gastrointestinal cancer in iran. therefore, the aim of this study was mapping stomach cancer rate in iran using area-to-area poisson kriging.   methods: data of 336 cities in iran was analyzed that was gathered by the ministry of health and medical education (in the non-infectious diseases management center) from 2003 to 2007. area-to-are...

Dermatology is a medical field which stands to be heavily augmented by the use of artificial intelligence techniques. Diseases are visually screened for, and many disease diagnoses are performed strictly with an in-clinic visual examination. Discerning between skin lesions is difficult the difference between skin cancer (melanoma, carcinoma) and benign lesions (nevi, seborrheic keratosis) is mi...

Abstract Background The emergence of immune checkpoint inhibitors (ICI’s) in the past decade has proven transformative area immuno-oncology. PD-1 / PD-L1 axis been particularly well studied and monoclonal antibodies developed to block either receptor (anti PD-1) or its associated ligand PD-L1) can generate potent anti-tumour immunity certain tumour models. However, many “immune cold” tumours re...