Antifungal testing results from the SENTRY Antimicrobial Surveillance Program (2008 to 2009) were analyzed for regional variations of invasive Candida species infections. Among 2,085 cases from the Asian-Pacific (APAC) (51 cases), Latin American (LAM) (348 cases), European (EU) (750 cases), and North American (NAM) (936 cases) regions, Candida albicans predominated (48.4%), followed by C. glabr...

candida glabrata was thought to be a primarily non-pathogenic organism. however, with the ever-increasing population of immunocompromised individuals, it is considered to be an opportunistic pathogen. patients with spinal cord injuries often using a long-term urinary catheter and are high risk for urinary tract infections. this case report describes a patient with spinal cord injury (thoracic r...

Background and Objectives Colonization of Candida species is common in pediatric patients admitted to hematology-oncology wards. The aim of this study was to identify colonized Candida species and their susceptibility patterns in hematologic pediatric patients. Materials and Methods Samples were collected from mouth, nose, urine and stool of the patients admitted to five university hospitals ...

BACKGROUND Different yeast species have different susceptibilities to commonly prescribed antifungal drugs. Thus, it is important to accurately determine the species of pathogenic yeasts, especially when more than one species are in a specimen. METHODS Clinically significant yeast isolates were collected via the Taiwan Surveillance of Antimicrobial Resistance of Yeasts from July to September ...

this overt inverse relationship has not been reported before now, C. albicans with targeted deletion of ERG3 or ERG11 showed increased susceptibility to amphotericin B and resistance to azoles. 11 The altered azole MICs for these sequential azole-naive isolates suggest that azole resistance in this clone may be associated with amphotericin B resistance mechanisms. This may be attributed to the ...

We characterized the oxidative stress response of Candida glabrata to better understand the virulence of this fungal pathogen. C. glabrata could withstand higher concentrations of H(2)O(2) than Saccharomyces cerevisiae and even Candida albicans. Stationary-phase cells were extremely resistant to oxidative stress, and this resistance was dependent on the concerted roles of stress-related transcr...

The infection rate of arteriovenous (AV) grafts is high, but fungal etiology is rare. Only five cases of graft infection due to Candida albicans (C. albicans) or C. tropicalis have been described in the literature. Herein, we report the first case of AV graft infection caused by C. glabrata. A 60-year-old woman on maintenance hemodialysis for end-stage renal disease was admitted because of inte...

BACKGROUND Candida genus has various species. The incidence of C. glabrata has presented itself with more frequency over the past years with clinical importance. METHODS A case study was made to determine the frequency of C. glabrata in 468 patients who presented clinical symptomatology for vulvovaginal candidiasis and the in vitro response for fluconazole using two methods: diffusion in agar...

BACKGROUND Candida species are emerging as a potentially pathogenic fungus in patients with broncho-pulmonary diseases. The synergistic growth promoting association of Candida and Mycobacterium tuberculosis has raised increased concern for studying the various Candida spp . and its significance in pulmonary tuberculosis patients during current years. AIMS This study was undertaken with the ob...