Meningoencephalitis (ME) is a common inflammatory disorder of the central nervous system in dogs. Clinically, ME has both infectious and non-infectious causes. In the present study, a multiplex quantitative real-time polymerase chain reaction (mqPCR) panel was optimized for the detection of eight canine neurologic pathogens (Blastomyces dermatitidis, Cryptococcus spp., Neospora caninum, Borreli...

Johnny D. Hoskins is Professor of Veterinary Clinical Medicine, School of Veterinary Medicine, Louisiana State University, Baton Rouge. John D, Rhoades is Professor of Veterinary Medicine and Coordinator of Public Programs at the school. canine distemper strains vary greatly. In the early stages it is characterized by discharges from eyes and nose and signs referable to digestive and respirator...

BACKGROUND Infectious diseases have contributed to the decline and local extinction of several wildlife species, including African wild dogs (Lycaon pictus). Mitigating such disease threats is challenging, partly because uncertainty about disease dynamics makes it difficult to identify the best management approaches. Serious impacts on susceptible populations most frequently occur when generali...

The Canine Distemper Virus (CDV) is the causative agent of a complex infection present in wide range hosts. It pathogen that affects various orders species, including primates, cetaceans, and families carnivores. should be noted virus can transmitted to wildlife, aquatic carnivores, through contact with domestic canids. This route transmission increasingly common, due fact species invade habita...

Two independent cDNA clones, identified as representing the mRNA of the nucleocapsid protein gene of peste-des-petits-ruminants virus, were sequenced. The longest insert was 1662 nucleotides, not counting the poly(A) tail, and it was estimated that about 21 nucleotides were missing from the complete gene sequence. The sequence contained one long open reading frame encoding a protein of 525 amin...

1. An epizootic disease of ferrets with a very high case fatality rate is described. 2. By the use of suitable material the natural disease can be transmitted experimentally. 3. The primary causative agent of the disease is a filterable virus. 4. Secondary invasion by bacteria of the respiratory tract of infected animals frequently occurs. The most important secondary invader is hemolytic strep...

Wild carnivores are often exposed to diseases via contact with peridomestic host species that travel through the wildland-urban interfaces. To determine the antibody prevalences and relationships to human activity for two common canid pathogens, we sampled 99 wolves (Canis lupus) from 2000 to 2008 for antibodies to canine parvovirus (CPV) and canine distemper virus (CDV) in Banff and Jasper Nat...

We have previously shown that canine signaling lymphocyte activation molecule (SLAM; also known as CD150) acts as a cellular receptor for canine distemper virus (CDV). In this study, we established Vero cells stably expressing canine SLAM (Vero.DogSLAMtag cells). Viruses were isolated in Vero.DogSLAMtag cells one day after inoculation with spleen samples from five out of seven dogs with distemp...

Canine distemper virus (CDV) is the cause of canine distemper (CD) which is a severe and highly contagious disease in dogs. In the present study, a duplex reverse transcription polymerase chain reaction (RT-PCR) method was developed for the detection and differentiation of wild-type and vaccine strains of CDV. Four primers were designed to detect and discriminate the two viruses by generating 6...

CANINE DISTEMPER is an acute, highly contagioui?, febrile disease caused by a filtrable virus and affecting principally young dogs. The disease is characterized by a catarrhal inflammation of all the mucous membranes of the body, which is frequently accompanied by nervous symptoms and pustular eruptions of the skin. It has its human counterpart in the form of influenza, which, though not identi...