Abstract Objective The aim of this study was to investigate the potential association rs11206510 in PCSK9 gene with coronary artery disease (CAD) and myocardial infarction (MI) Bulgarians. Materials Methods current analysis included 261 patients angiographically documented CAD (153 MI 108 without MI) 496 population – based controls. Genomic DNA extracted from venous blood samples. selected poly...

BACKGROUND Randomized trials of percutaneous coronary intervention (PCI) versus coronary artery bypass graft (CABG) routinely exclude patients with chronic kidney disease (CKD). OBJECTIVES This study evaluated outcomes of PCI versus CABG in patients with CKD. METHODS Patients with CKD who underwent PCI using everolimus-eluting stents were propensity-score matched to patients who underwent i...

Survival after an acute coronary syndrome has greatly improved because of advances in thrombolytic therapy, stabilization of the culprit lesion such as with coronary stents, and the use of pharmacological approaches to prevent recurrent thrombotic and arrhythmic events. Despite these approaches, however, myocardial injury culminating in myocardial infarction (MI) continues to be an all too comm...

BACKGROUND Patients who present with myocardial infarction (MI) and unprotected left main coronary artery (ULMCA) disease represent an extremely high-risk subset of patients. ULMCA percutaneous coronary intervention (PCI) with drug-eluting stents (DES) in MI patients has not been extensively studied. METHODS In this retrospective multicenter international registry, we evaluated the clinical o...

OBJECTIVES The investigators undertook a systematic, comprehensive analysis of the therapeutic response and clinical outcomes of reperfusion therapy for acute ST-segment elevation myocardial infarction (STEMI) in 5,470 patients from the Assessment of the Safety and Efficacy of a New Thrombolytic Regimen (ASSENT)-3 trial. BACKGROUND Prompt effective reperfusion therapy for acute STEMI may atte...

Motor imagery (MI) electroencephalograph (EEG) signals are widely applied in brain-computer interface (BCI). However, classified MI states are limited, and their classification accuracy rates are low because of the characteristics of nonlinearity and nonstationarity. This study proposes a novel MI pattern recognition system that is based on complex algorithms for classifying MI EEG signals. In ...

PURPOSE It remains controversial whether mini-incision (MI) benefits patients in total hip arthroplasty (THA). We performed a meta-analysis of randomized controlled trials (RCTs) to assess the effects of MI on surgical and functional outcomes in THA patients. METHODS A systematic electronic literature search (up to May 2013) was conducted to identify RCTs comparing MI with standard incision (...

The indication for prophylactic temporary and permanent pacing during acute myocardial infarction (MI) complicated by bundle branch block is high risk of progression via a Type II pattern to second or third degree (high degree) AV block during hospitalization or follow-up. In this study, determinants of high degree AV block during hospitalization and sudden death or recurrent high degree block ...

BACKGROUND Brain-derived neurotrophic factor (BDNF) is associated with coronary artery diseases. However, its role and mechanism in myocardial infarction (MI) is not fully understood. METHODS Wistar rat and Kunming mouse model of MI were induced by the ligation of left coronary artery. Blood samples were collected from MI rats and patients. Plasma BDNF level, protein expression of BDNF, tropo...

Let (W,S) be a Coxeter system, let S = I ∪ J be a partition of S such that no element of I is conjugate to an element of J , let J̃ be the set of WI -conjugates of elements of J and let W̃ be the subgroup of W generated by J̃ . We show that W = W̃ ⋊WI and that J̃ is the canonical set of Coxeter generators of the reflection subgroup W̃ of W . We also provide algebraic and geometric conditions for an e...