نتایج جستجو برای: cap oseltamivir
تعداد نتایج: 24776 فیلتر نتایج به سال:
BACKGROUND Although influenza virus resistance to the neuraminidase inhibitor zanamivir is reported less frequently than is resistance to the neuraminidase inhibitor oseltamivir in clinical settings, it is unknown whether this difference is due to the limited use of zanamivir or to an inherent property of the drug. We therefore compared the prevalence of drug-resistant viruses and virus sheddin...
OBJECTIVE To assess the efficacy and safety of RDNI in the treatment of seasonal influenza. RESULTS 1575 participants were screened and 229 completed the study and had a RT-PCR laboratory confirmation of influenza virus infection. Fever alleviation time was 2 and 6 hours, and fever clearance time was 27 and 47 in RDNI and oseltamivir, with significant difference between two groups. Total scor...
INTRODUCTION In October 2009, the first outbreak of pandemic influenza A(H1N1) 2009 virus in Madagascar occurred at a school in Antananarivo. Among the first 12 cases, five were reported in boarding pupils at the school. The school closed 10 days into the outbreak. Mass oseltamivir prophylactic treatment was used to contain the outbreak. This study aimed to determine the transmission of infect...
Arctiin and its aglucone, arctigenin from the fruits of Arctium lappa L. showed potent in vitro antiviral activities against influenza A virus (A/NWS/33, H1N1) (IFV). Based on the data from time-of-addition experiments and on release tests of progeny viruses, arctigenin was assumed to interfere with early event(s) of viral replication after viral penetration into cells, and to suppress the rele...
OBJECTIVE To determine if oseltamivir with standard therapy for canine parvoviral enteritis ameliorates disease morbidity, mortality, or both; to document significant adverse effects associated with its use. DESIGN Prospective, randomized, blinded, placebo-controlled clinical trial. SETTING University veterinary teaching hospital. ANIMALS Thirty-five dogs. INTERVENTIONS Standard therapy...
در طول دهه گذشته، مطالعات متنوعی برای توصیف نقش خواب در تثبیت حافظه و نحوه شکل پذیری ارتباطات سیناپسی مغز، صورت پذیرفته است. این یافته ها نشان می داد که خواب و مراحل گوناگون آن، به فرایندهای نهفته ای که در تثبیت هر دو گونه حافظه اخباری و غیر اخباری نقش دارند، کمک می کند. تا به امروز گزارش هایی درباره ی اثرات خواب بر روی حافظه عاطفی، منتشر شده است. این گزارش ها نشان می دهد بهبود، تثبیت و یکپارچ...
A simple and rapid micellar electrokinetic chromatography (MEKC) method was developed for the analysis of an antiviral drug, oseltamivir, and its hydrolyzed product in Tamiflu capsules. Background electrolytes consisted of boric acid 10 mM, pH 10, and sodium dodecyl sulphate (SDS) 40 mM. The limit of detection (LOD) and limit of quantification (LOQ) of oseltamivir were 1.7 and 8.0 microg/ml, re...
BACKGROUND Pandemic influenza A H1N1 2009 virus presents a new challenge to health authorities and communities worldwide. In Argentina, the outbreak was at its peak by the end of June 2009, during the southern winter. A systematic analysis of samples from patients with pandemic H1N1 2009 studied in our laboratory (Virology Laboratory, Hospital de Niños R Gutiérrez, Buenos Aires, Argentina) dete...
In the absence of a parenteral drug, oral oseltamivir is currently recommended by the WHO for treating H5N1 influenza. Whether oseltamivir absorption is adequate in severe influenza is unknown. We measured the steady state, plasma concentrations of nasogastrically administered oseltamivir 150 mg bid and its active metabolite, oseltamivir carboxylate (OC), in three, mechanically ventilated patie...
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