Carbonyl-carbonyl interactions between adjacent backbone amides have been implicated in the conformational stability of proteins. By combining experimental and computational approaches, we show that relevant amidic carbonyl groups associate through an n→π* donor-acceptor interaction with an energy of at least 0.27 kcal/mol. The n→π* interaction between two thioamides is 3-fold stronger than bet...

In this study, antioxidative activities of aqueous extract of Biarum bovei (BBE) in stabilizing of canola oil during storage at 20°C was evaluated. For this purpose, the total phenolic (TP), flavonoids (TFC), and tocopherol content (TTC) of the extract were determined and β-carotene bleaching system was used to assess the antioxidant efficacy of BBE. The amount of TP, TFC, and TTC in BBE indica...

The aim of present study was to evaluate antioxidant efficacy of pussy willow extract (PWE) and essential oil (PWEO) in stabilization of sunflower oil (SFO) during ambient storage (60 days at 25°C). Initially, total phenolic (TP) and total flavonoid (TF) contents were evaluated. Then, PWE, PWEO, and TBHQ were added to SFO. Peroxide value (PV), carbonyl value (CV), total polar compound (TPC), ac...

Administration of nickel carbonyl to rats by intravenous in jection (2 mg Ni/100 gm body weight) inhibited the induction of hepatic tryptophan pyrrolase by cortisone but not by tryptophan. Cortisone induction was impaired on the day after admin istration of nickel carbonyl. It reached a minimum at 2 days and remained diminished for 5 days. The average activity of hepatic tryptophan pyrrolase in...

Protein carbonyls are widely analysed as a measure of protein oxidation. Several different methods exist for their determination. A previous study had described orders of magnitude variance that existed when protein carbonyls were analysed in a single laboratory by ELISA using different commercial kits. We have further explored the potential causes of variance in carbonyl analysis in a ring stu...

The objective of the present study was to evaluate protein carbonyl concentration as a predictor of AKI development in patients with septic shock and of renal replacement therapy (RRT) and mortality in patients with SAKI. This was a prospective observational study of 175 consecutive patients over the age of 18 years with septic shock upon Intensive Care Unit (ICU) admission. After exclusion of ...

The present QSAR study has attempted to explore the structural and physicochemical requirements of ligands N,N-dialkyl-2-phenylindol-3-yl-glyoxylamides for binding with peripheral benzodiazepine receptor (PBR). The calculated partition coefficient values show parabolic relations with the PBR binding affinity, suggesting that the binding affinity increases with increase in the partition coeffici...

Acceptor-less alcohol dehydrogenation reaction allows the co-production of added-value carbonyl compounds and H2 from alcohols. Focusing on supported Ru Cu catalysts, we evaluated support effect 2-octanol 1-octanol identified side products as resulting aldolisation coupling. The most active selective catalysts were then tested aliphatic vicinal-diol octan-1,2-diol highest conversion was reached...

Baeyer–Villiger oxidation can synthesize a series of esters or lactones that have essential application value but are difficult to be synthesized by other methods. Cycloketones oxidized using molecular oxygen, peroxy acids, hydrogen peroxide as an oxidant. Hydrogen is one the environmental oxidants. Because weak ability peroxide, Bronsted acids and Lewis used catalysts activate carbonyl ketones...