This research aims to assess contamination status of water and sediment in Sabalan dam reservoir (SDR) evaluate the impact withdrawal depths on carcinogenic non-carcinogenic risks metals for exposed people. Results metal pollution indices revealed some degree reservoir, especially associated with arsenic. Risk assessment SDR materials through different scenarios depth that consuming from 10 m c...

Using archived specimens, we evaluated a new automated real-time PCR assay (BD Diagnostics) that detects all carcinogenic human papillomaviruses (HPV) and provides HPV genotyping for seven of them, including HPV16 and HPV18, the two most carcinogenic HPV genotypes. We found comparable results with Hybrid Capture 2 (HC2) for detection of carcinogenic HPV (n = 473) and with Linear Array and Line ...

So Oc on Beginning with Percival Pott’s 1775 observation of an excess of scrotal cancer among young chimney sweeps in London, specific agents and processes in the industrial environment are some of the most wellstudied and well-recognized causes of human cancer. Of the 935 agents and exposure circumstances evaluated by the International Agency for Research on Cancer (IARC), over 400 are now lis...

The European Food Safety Authority has prepared a draft for a harmonised strategy for the risk assessment of genotoxic and carcinogenic substances and presented this draft for discussion. The concept examines the exposure of the consumer to a specific substance and compares this with the carcinogenic effect of a defined dose in an animal experiment. Genotoxic and carcinogenic compounds are thus...

brought to visible tumors. Mottram (10) observed tumor production in mouse skin after exposing it to a single treatment with a carcinogenic hydrocarbon, followed by re peated applications of croton oil. Later, Berenblum and Shubik (3) adapted this method to a quantitative approach to the study of chemical carcinogenesis. According to this method, the actual number of tumors produced were said t...

The ability of croton oil to elicit epithelial tu mors in mice in areas previously treated with subcarcinogenic amounts of carcinogenic hydrocar bons is a well documented fact. In the typical ex periment tumors are initiated in the skin of mice by the single application of a solution of some car cinogenic hydrocarbon at a level that induces few if any tumors. The repeated application of croton ...

The usefulness of mouthwash as a transport medium for cervical specimens for carcinogenic human papillomavirus (HPV) DNA testing has not been evaluated. Two cervical specimens were collected from each of 34 patients, with one placed in mouthwash (Scope, Proctor and Gamble, Inc.) and the other in a liquid cytology medium commonly used for HPV DNA testing in alternating order. Paired specimens we...

The increased incidence of cancer over the last 50-60 years may be largely attributed to two factors: the ageing of the population and the diffusion of agents and situations presenting carcinogenic risks. Today, we have entered into a new era in which populations are ever-increasingly exposed to diffuse carcinogenic risks, present not only in the occupational, but also in the general environmen...

The present study was undertaken to investigate the carcinogenic reaction of rats trcated with two different and differently acting carcinogens. This seemed to be of interest for various reasons. First, it would be possible to study the influence of one carcinogenic agent on the action of another. Although there are numerous publications on the action of carcinogenic substances on established t...