نتایج جستجو برای: carcinogens
تعداد نتایج: 10821 فیلتر نتایج به سال:
Colon carcinogens produce a variety of nuclear anomalies including pyknotic, karyorrhectic, and micronucleated cells in the colonie epithelium within a few hr. Two model carcinogens, 1,2dimethylhydrazine and 7-rays, have been used to determine appropriate techniques, conditions, and scoring critiera for de tecting such nuclear anomalies most efficiently. The results show that a rapid and sensit...
Tobacco smoking causes millions of cancer deaths annually. Tobacco smoke is a complex mixture of thousands of chemicals including many known animal carcinogens. Because many carcinogens from DNA adducts in target animal or human tissues, the detection of the formation of adducts using such methods as postlabeling, immunoassay, fluorescence spectroscopy, and mass spectrometry is a means of monit...
Colon carcinogens produce a variety of nuclear anomalies including pyknotic, karyorrhectic, and micronucleated cells in the colonic epithelium within a few hr. Two model carcinogens, 1,2-dimethylhydrazine and gamma-rays, have been used to determine appropriate techniques, conditions, and scoring criteria for detecting such nuclear anomalies most efficiently. The results show that a rapid and se...
Introduction Radiation that has sufficient energy to remove electrons from atoms is called “ionizing radiation.” Ionization results in the production of negatively charged free electrons and positively charged ionized atoms. Ionizing radiation can be classified into two groups: photons (includes X-radiation and gamma radiation) and particles (includes alpha and beta particles and neutrons). The...
BACKGROUND The worldwide mortality and morbidity from lung cancer, leukemia, and malignant mesothelioma arising from occupational exposures to carcinogens are described. Cases reported in the year 2000 that resulted from relevant past and current exposures are assessed. METHODS The proportions of workers exposed to the carcinogens of interest, and their levels of exposure, were estimated usin...
The purpose of this review is to stimulate new ideas regarding low-dose environmental mixtures and carcinogens and their potential to promote invasion and metastasis. Whereas a number of chapters in this review are devoted to the role of low-dose environmental mixtures and carcinogens in the promotion of invasion and metastasis in specific tumors such as breast and prostate, the overarching the...
The current literature on non-genotoxic renal carcinogens and the associated neoplastic and preneoplastic lesions has been reviewed in order to determine their occurrence and predictive nature with regard to tumor formation. In addition the mechanisms involved in the genesis of renal tumors are discussed. A more generalized classification of preneoplastic and neoplastic renal lesions was introd...
Strategies for controlling occupational exposure to chemical carcinogens are set out in the European Union Carcinogens Directive and in national legislation such as the British Control of Substances Hazardous to Health Regulations. While such legislative requirements must apply to all occupational chemical carcinogens, it is argued that priority should be given to controlling those agents that ...
Source Identification of VOCs and their Environmental Health Risk in a Petrochemical Industrial Area
Ambient VOCs in the vicinity of a petrochemical industrial area were analyzed for their health impact and potential emission sources. Comprehensive measurements conducted based on U.S. EPA TO-15. Potential carcinogenic non-carcinogenic inhalation risks evaluated by comparing measured concentrations with unit risk (IUR) reference concentration (RfC). The results indicated that high occurred from...
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