materials and methods the expression of gp73 was investigated in 88 cancerous and self-control non-cancerous tissues using tissue microarrays with immunohisto- chemistry and was confirmed by western blotting. circulating gp73 levels were detected in the sera of 281 patients with liver diseases using enzyme-linked immunosorbent assay. results the levels of circulating gp73 expression in the hcc ...

prior investigators demonstrated helicobacter pylori as a risk factor of liver diseases. in this study association between h. pylori and hepatocellular carcinoma was investigated. patients and methods totally, 59 specimens of liver were collected from two health care centers affiliated to shahid beheshti university of medical sciences, including 22 specimens of hepatocellular carcinoma, 18 spec...

in females, the most common cancer is breast carcinoma in which squamous cell carcinoma (scc) is a rare type of malignancy. histologically, infiltrating ductal carcinoma is the most common type and lobular, mucinous, and medullary types have lower incidence. pure scc of the breast can originate from the skin, nipple, or epithelium of a deep‑seated dermoid cyst or squamous metaplasia on chronic ...

metastatic   tumors in the nose and paranasal sinuses are infrequent. the origin of this metastatic tumors are often renal cell carcinoma. we present one case of metastatic renal cell carcinoma   to the nose and paranasal sinuses ,4 years after initial nephrectomy and diagnosis of stage t1n0m0 clear cell carcinoma. the patient complained of nasal obstruction and recurrent epistaxis   who was tr...

background and aims. there is no report on the apoptotic impact of allium sativum l. (garlic) on the oral squamous cell carcinoma (kb); hence, this study was designed to survey the apoptotic effects of garlic fresh juice (gfj) on the kb cells. materials and methods. mtt assay (microculture tetrazolium assay) was carried out to evaluate the cytotoxicity of gfj on kb cells. furthermore, tunel (te...

background and aims. various morphologies are seen in different salivary gland tumorsor within an individual tumor, and the lesions show divers biological behaviors. experimental results support the hypothesis that increased crkii proto-oncogene is associated with cytokine-induced tumor initiation and progression by altering cell motility signaling pathway. the aim of this study was to assess t...

paragangliomas are tumors that originate from extra-adrenal medullary neural crest derivatives. they are rarely located in retroperitoneal space. these tumors are often discovered incidentally during imaging studies performed for other reasons.periampullary cancers include adenocarcinomas arising from the pancreas, ampulla of vater, duodenum or distal common bile duct. the exact site of origin ...

objectives we undertook this study to compare the results of hormone receptor assessment in cnb and surgical samples on our patients. patients and methods hormone receptor status was determined in cnb and surgical samples in breast cancer patients whose cnb and operation had been performed in this institute from 2009 to 2011 and had not undergone neoadjuvant chemotherapy. results about 350 pati...

hepatocellular carcinoma (hcc) is very rare during pregnancy and has a worse prognosis in pregnant women compared to those who are not pregnant. we present a case of hcc in a 41- year-old pregnant patient who was referred to our academic hospital. the patient presented with chief complaints of abdominal pain, jaundice, edema and hypertension. laboratory results were notable for elevated liver e...

background: considering the ease of administration of capecitabne instead of infusional 5fu for concurrent  radiochemotherapy (rct) of rectal cancer, the use of capecitabine has increased significantly in our radiation oncology department in the past years. thus we decided to compare the safety and survival with these 2 drugs by a retrospective review. methods: files of all patients receiving r...