Definitions of shock and resuscitation endpoints traditionally focus on blood pressures and cardiac output. This carries a high risk of overemphasizing systemic hemodynamics at the cost of tissue perfusion. In line with novel shock definitions and evidence of the lack of a correlation between macro- and microcirculation in shock, we recommend that macrocirculatory resuscitation endpoints, parti...

During its 36. Annual Meeting from June 9.-10., 2017, in Greifswald (Germany), the German Society for Clinical Microcirculation and Hemorheology hosted the 5th MIDAS Microcirculation Meeting (3M). MIDAS stands for Microcirculation Diagnostics and Applied Studies research group, founded 2012 in Halifax (Canada). This international group consists of basic scientists and clinical researchers with ...

35. Safar P, Stezaski W, Nemoto EM: Amelioration of brain 37. damage after 12 minutes cardiac arrest in dogs. Arch Neurol 33: 91-95, 1976 36. Sundt TM Jr, Waltz AG: Hemodilution and anticoagulation. 38. Effects on the microvasculature and microcirculation on the cerebral cortex after arterial occlusion. Neurology 17: 230-238, 39. 1967 Thorsen G, Hint H: Aggregation, sedimentation and intravascu...

Adipose tissue secretes a number of cytokines, referred to as adipokines. Intensive studies conducted over the last two decades showed that adipokines exert broad effects on cardiac metabolism and function. In addition, the available data strongly suggests that these cytokines play an important role in development of cardiovascular diseases. Epicardial adipose tissue (EAT) has special propertie...

BACKGROUND Angiopoietin (Ang)-1 is an angiogenic growth factor that counteracts the permeability and proinflammatory effects of vascular endothelial growth factor and other proinflammatory cytokines. Recently, we demonstrated that vascular endothelial growth factor enhances cardiac allograft arteriosclerosis. Here, we studied the roles of Ang1, its natural antagonist Ang2, and their receptor Ti...

This article reviews the experience available to date on microcirculation assessment in cancer of the cervix including correlation studies of magnetic resonance (MR) microcirculatory parameters with histo-morphometric predictors and direct correlation with patient outcome. The data suggest that MR microcirculation parameters do not always correlate with histo-morphometric parameters, while ther...

BACKGROUND Monitoring of the microcirculation may add additional information in terms of improving the adequacy of hemodialysis (HD) for patients. Withdrawal of liquid and complement activation during a HD session reduces the external pressure on the microcirculation and leads to an increased dilatation of the peripheral capillaries. The purposes of this study were to assess the effect of a sin...

The method of intravenous laser blood irradiation was first introduced into therapy by the Soviet scientists E.N.Meschalkin and V.S.Sergiewski in 1981 [32]. Originally this method was developed for the treatment of cardiovascular diseases. Improvement of rheologic properties of the blood as well as improvement of microcirculation and reduction of the area of infarction had been proved. Further ...