Correspondence to: Professor Filippo Crea, Istituto di Cardiologia, Università Cattolica del Sacro Cuore, Largo A. Gemelli, 8, 00168 Roma, Italy; [email protected] _________________________ A mong patients undergoing coronary angiography because of angina typical enough to suggest coronary artery disease, 10–30% are found to have ‘‘normal’’ or ‘‘near normal’’ epicardial coronary arteries at ...

Correspondence to: Professor Filippo Crea, Istituto di Cardiologia, Università Cattolica del Sacro Cuore, Largo A. Gemelli, 8, 00168 Roma, Italy; [email protected] _________________________ A mong patients undergoing coronary angiography because of angina typical enough to suggest coronary artery disease, 10–30% are found to have ‘‘normal’’ or ‘‘near normal’’ epicardial coronary arteries at ...

The most frequent foetal chromosomal abnormalities involve the autosomes 21, 18, 13, and sex chromosomes X and Y. Aneuploidy or alterations in copy number of these chromosomes, including trisomy 21 (Down syndrome), trisomy 18 (Edwards’ syndrome), trisomy 13 (Patau’s syndrome), 45,X (Turner’s syndrome), and 47,XXY (Klinefelter’s syndrome) account for 80% of clinically significant chromosomal abn...