background: the areas of the bed nucleus of the stria terminalis (bst) with a high density of estrogen receptors are involved in cardiovascular regulation and send axonal projections to the rostroventrolateral medulla (rvlm). we aimed to find the contribution of the rvlm to cardiovascular responses elicited by glutamate microinjection into the bst. methods: experiments were done in α-chloralose...

AIM To assess the total cardiovascular risk of the Bulgarian urban population. METHODS A representative sample of Bulgarian urban population (n=3810, response rate 68.3%) from five Bulgarian cities was included in a cross-sectional observation study performed in the period 2005-2007. A detailed cardiovascular risk assessment was performed by general practitioners and a total 10-year risk of a...

Introduction: Job stress is one of the main characteristics of modern life which is increasing and has been recognized as an important risk factor of cardiovascular diseases. The present study was conducted to determine the association between job stress at work environment and cardiovascular diseases. Materials and methods: A number of 300 persons including 150 cases and 150 controls were con...

Objective(s): The 5-hydroxytryptamine1A (5-HT1A) receptor is one of the serotonin receptors in the brain, which regulates cardiovascular responses, especially in hemorrhage. Presence of this receptor in the cuneiform nucleus (CnF) has been shown. The present study evaluates the cardiovascular effect of this receptor of the CnF in normal and hypotensive hemorrhagic rats...

abstract  introduction: hypertension is a major cause of cardiovascular disease and the prevalence of hypertension shows a linear increase with aging so that it increases by 10 percent every 10 years. this study was conducted to investigate the causes of uncontrolled blood pressure in people aged over 65 years. methods: this descriptive case-control study was conducted at isfahan amin hospital ...

Background: The presence of nitric oxide (NO) in the cuneiform nucleus (CnF) has been previously shown. In this study, NG-nitro-L-arginine methyl ester (L-NAME) (an inhibitor of NO synthase), L-arginine (L-Arg) (a precursor of NO), and sodium nitroprusside (SNP) (a donor of NO) were microinjected into the CnF and cardiovascular responses were investigated. Methods: Seventy male rats were divide...

Objective: Angiotensin II (Ang II), the main product of renin-angiotensin system (RAS) has a well-known role in cardiovascular regulation. Over-production of Ang II is one of the important underlying mechanisms of hypertension. In this study, the effect of crocin on cardiovascular responses in rats with acute hypertension induced by Ang II was evaluated. Materials and methods: Rats were divided...