We sought to determine the effects of supplementary choline, carnitine and a combination of the two with or without exercise on serum and urinary carnitine and biochemical markers of fatty acid oxidation in healthy humans. Nineteen women were placed in three groups: 1) placebo, choline or carnitine preloading period of 1 wk followed by 2) supplementation with choline plus carnitine during wk 2-...

background: to determine any correlation between infertility and semen quality with concentrations of l-carnitine in human seminal plasma. methods: this case-control study performed in fatemieh hospital in hamadan, iran. seminal plasma of 72 infertile men and 80 men with proved fertility as a control group was investigated and l-carnitine level was determined using uv enzymatic test at 340 nm. ...

OBJECTIVES L-carnitine and dehydro-epiandrosterone (DHEA) independently promote mitochondrial energy metabolism. We therefore wondered if an age-related deficiency of L-carnitine or DHEA may account for the declining energy metabolism associated with age. METHODS we evaluated serum levels of L-carnitine and the sulphated derivative of DHEA (DHEAS) in cross-sectional study of 216 healthy adult...

Radioisotopic analyses for carnitine content were done on infant formula, formulas for tube feeding, food supplements, and chemically defined diets. The carnitine content of the diets depend on the protein source. Products whose main protein source is soy protein isolate, casein, or egg white solids contain 4 nmole carnitine per milliliter or less, with most of them containing undetectable amou...

BACKGROUND Ninety-five percent of the body carnitine pool resides in skeletal muscle where it plays a vital role in fuel metabolism. However, vegetarians obtain negligible amounts of carnitine from their diet. OBJECTIVE We tested the hypothesis that muscle carnitine uptake is elevated in vegetarians compared with that in nonvegetarians to maintain a normal tissue carnitine content. DESIGN F...

Objective: Diabetes causes free radical production, oxidative stress and alterations in mitochondrial enzymes and apoptosis. The purpose of this study was to investigate the effect of aerobic exercise and consumption of L-carnitine on BCL2 and some mitochondrial enzymes of the kidney in diabetic rats. Materials and Methods: In this experimental study, 45 male wistar rats (200-300 gr) were simp...

1. The optical rotatory dispersion of carnitine acetyltransferase is altered in the presence of l-carnitine or acetyl-l-carnitine. These changes, which include an increase in the reduced mean residue rotation at 233nm. ([M'](233)), suggest that substrate binding causes the enzyme to unfold. 2. CoA and acetyl-CoA have no immediate effect on [M'](233) and CoA has no effect on the change in this p...

abstract background: sperm cells extracted from testes (tese) have poor chromatin quality and motility. various substances are used in the laboratory to increase sperm motility and improve the art outcomes; however, there are few research which considered improving both sperm motility and chromatin quality. objective: the aim of this investigation was to evaluate the improvement of the testicul...