BACKGROUND Both airflow limitation and smoking are established cardiovascular risk factors. However, their interaction as risk factors for the development of atherosclerosis in coronary artery disease patients remains unclear. OBJECTIVES To evaluate the effect of the interaction between airflow limitation and smoking status on the severity of carotid atherosclerosis. METHODS We categorized ...

The propensity to develop atherosclerosis varies markedly among different sites in the human vasculature. To determine a possible cause for such differences in atherosclerosis susceptibility, a proteomics-based approach was used to assess the extracellular proteoglycan core protein composition of intimal hyperplasia from both the atherosclerosis-prone internal carotid artery and the atheroscler...

BACKGROUND This paper presents quantitative analysis of blood flow shear stress by measuring the carotid arterial wall shear stress (WSS) and the intima-media thickness (IMT) of experimental rabbits fed with high-fat feedstuff on a weekly basis in order to cause atherosclerosis. METHODS This study is based on establishing an atherosclerosis model of high-fat rabbits, and measuring the rabbits...

abstract introduction: non-invasive measurement of carotid intima media thickness (imt) has been noted as a marker for atherosclerosis and can serve as a predictor of cardiovascular accidents. the present study investigates the relationship between carotid imt and coronary artery disease (cad). method: this is a descriptive, analytical cross-sectional study of 300 individuals referring to isfah...

Fifty patients with coronary artery disease admitted to the National Institute of Cardiovascular Diseases (NICVD), Dhaka were screened for presence of carotid atherosclerosis by duplex ultrasound study during the period of July ’98 to Aug ’99. Out of 50 patients 34 patients (68%) had carotid lesions and normal carotids found in 16 patients (32%). Age range of patients with and without carotid l...

Introduction Identifying patients with carotid atherosclerosis at risk for ischemic stoke would greatly benefit patient outcomes. Recently, high-resolution methods have enabled MRI to noninvasively image the fine internal structure of the carotid plaque [1]. Some carotid plaque features, such as the presence of intraplaque hemorrhage (IPH) and thin or ruptured fibrous cap on multi-contrast weig...

UNLABELLED Intensive multifactorial treatment aimed at cardiovascular (CV) risk factor reduction in type 2 diabetic patients with microalbuminuria can diminish fatal and non-fatal CV. Plasma N-terminal (NT)-proBNP predicts CV mortality in diabetic patients but the utility of P-NT-proBNP in screening for atherosclerosis is unclear. We examined the interrelationship between P-NT-proBNP, presence ...

BACKGROUND Many studies have demonstrated that the geometry of the carotid bifurcation enables prediction of blood flow variation associated with atherosclerotic plaque formation. The phase angle between the arterial wall circumferential strain and its instantaneous wall shear stress is known as stress phase angle (SPA). This parameter is used to evaluate hemodynamic factors of atherogenesis. N...

This paper examines the association between trait anger and subclinical carotid artery atherosclerosis among 14,098 Black or White men and women, aged 48-67 years, in the Atherosclerosis Risk in Communities Study cohort, 1990-1992. Trait anger was assessed using the 10-item Spielberger Trait Anger Scale. Carotid atherosclerosis was determined by an averaged measure of the wall intimal-medial th...

the management of carotid artery stenosis reduces the risk of stroke and its related deaths.   management options include risk factor modification and medical therapy, carotid endarterectomy (cea), and carotid artery stenting (cas). although several randomized controlled trials (rcts), mostly conducted in late-1980s and mid-1990s, have proved cea to be effective in the prevention of ipsilateral...