Objective- To determine the effect of the transcutaneous electrical neural stimulation on healing of hip joint cartilage defect in rabbit.Design- Experimental in vivo study.Animals- 12 adult New Zealand rabbits were used.Procedures- Under effective the right femoral head was subluxated and the maximum accessible cartilage was denuded up to subchondral bone using dental bit in each rabbit. Then ...

introduction: to demonstrate surgical techniques and to compare the anatomical and functional outcomes between temporalis fascia and cartilage palisade grafting in type-i underlay tympanoplasty in patients with large/subtotal perforation.materials and methods:temporalis fascia and cartilage palisade grafting were conducted in group a and group b, respectively, each containing 30 patients with l...

background filler materials are gaining popularity in nonsurgical rhinoplasty the major advantages are the ability to camouflage the surface deformities, and also the soft and malleable consistency while the major drawback of the safe fillers such as hyaluronic acid is short durability. in this study, we evaluated the injectable cartilage shaving as an autologous filler material for correction ...

Angiogenesis and tumor growth were inhibited in two different animal models by regional infusion of a partially purified cartilage extract. In rabbits bearing corneal implants of V2 carcinoma and receiving the inhibitor, vascular growth rates were < 3% of those in control animals receiving either Ringer's solution or bovine trypsin inhibitor (Trasylol). Subconjunctival B16 melanoma implants in ...

A 25-kDa homodimeric protein was purified from demineralized bovine bone extract and identified as activin A. The bovine bone activin enhanced formation of ectopic bone in rat subcutis when implanted in combination with partially purified bovine bone morphogenetic protein (BMP-2, BMP-3) in collagen/ceramic carrier. The implants, removed at 14 days, contained markedly elevated levels of alkaline...

articular cartilage, the load-bearing tissue of the joint, has limited repair and regeneration ability. the scarcity of treatment modalities for large chondral defects has motivated researchers to engineer cartilage tissue constructs that can meet the functional demands of this tissue in vivo. cartilage tissue engineering requires 3 components: cells, scaffold, and environment. owning to their ...

Introduction. Loss of the large aggregating proteoglycan, aggrecan, from articular cartilage is a central pathophysiological features of joint diseases such as osteoarthritis (OA). Depletion of aggrecan from the cartilage as a result of proteolytic degradation occurs as an early event in disease progression and exposes the tissue to mechanical disruption. Matrix metalloproteinases (MMPs) and ag...

osteoarthritis is the most common joint disease.the main pathologic manifestation of disease is local destruction of cartilage in diarthrodial joint. new bone formation in marginal surface of the joint is a sign progressive disease. many systemic and local factors are introduced in initiate and progression of osteoarthritis include: age, sex, weight, race, genetic background, bone densitometry,...

In previous studies, we have shown the relaxatory effect of grape leaf (Vitis vinifera) extract on isolated ileum, uterus and aorta. In rat aorta it was revealed that the NO and endothelium are involved in the relaxation induced by grape leaf extract. The aim of present study was to investigate the effect of the Vitis vinifera leaf hydroalcoholic extract (VLHE) on rat trachea precontracted by A...