Purpose. To describe the impact of COVID-19 pandemic on TB care. Results. Active detection was affected by restrictions population mobility („lockdown”), which led to an increase in proportion patients diagnosed passively and post-mortem, as well number newly with fibro-cavitary tuberculosis. (with without lockdown) has a decrease notified new cases adults. The hospitalizations inpatient clinic...

Congenital tuberculosis is a rare disease with a high mortality rate. Congenital tuberculosis is considered the result of mother-to-child transmission from the placenta to the fetus, through the ingestion of the amniotic fluid, or via transplacental transmission through the umbilical vein. Given the non-specific clinical signs of tuberculosis, it is usually difficult to diagnose it. The case of...

Different clinical outcomes of tuberculosis can be related to the balance between cell-mediated and humoral immunity. In this prospective study we examined the humoral immune responses to recombinant and native mycobacterial antigens in relation to clinical presentations of pulmonary TB. Two hundred and fifteen serum samples were examined including: non-cavitary (n=120), cavitary (n=65), caseou...

Introduction Rasmussen’s aneurysm is an inflammatory pseudoaneurysmal dilatation of a branch the pulmonary artery adjacent to tuberculous cavity. It often presents with hemoptysis resulting from its rupture. Massive seen in giant aneurysms rare but life-threatening complication cavitary tuberculosis. Aim In this case, we aimed present case rasmussen that did not bleed and was diagnosed incident...

BACKGROUND Diabetes mellitus has been reported to modify the presenting features of pulmonary tuberculosis, but there are varying data, particularly regarding the association with lower lung field involvement. OBJECTIVES To determine whether diabetes mellitus alters the clinical and radiographic manifestations of tuberculosis in nonimmunocompromised hosts and to define the determinants of low...

Klebsiella species infrequently cause acute community acquired pneumonia (CAP). The chronic form of the disease caused by K. pneumoniae (Friedlander's bacillus) was occasionally seen in the pre-antibiotic era. K. oxytoca is a singularly uncommon cause of CAP. The chronic form of the disease caused by K. oxytoca has been documented only once before. A 50-year-old immunocompetent male smoker pres...

The authors present two case reports of necrotizing pulmonary aspergillosis. This disease is part of a spectrum of clinical conditions caused by the inhalation of Aspergillus spores. The necrotizing pulmonary aspergillosis (NPA) corresponds to an indolent, destructive process of the lung due to invasion by Aspergillus species, usually A. fumigatus. The diagnosis is confirmed by a histological d...

The patient was a 71-year-old man. Two months after using prednisolone at a dose of 80 mg/day for the treatment of drug-induced interstitial pneumonia induced by chemotherapy following lung cancer surgery, his chest x-ray fi lm showed cavitary shadows, and Nocardia farcinica was detected from subcutaneous abscess, sputum, urine, and blood cultures. Thus, disseminated nocardiosis involving multi...

Mycobacterium celatum has been shown to cause disease in immunocompromised patients. We report a case of serious pulmonary infection caused by M. celatum in an apparently immunocompetent patient and review the characteristics of two other reported cases. Clinical and radiologic symptoms and signs included cough, malaise, and weight loss associated with cavitary lesions and pulmonary infiltrates...

A 62-year-old male presented with productive cough, weight loss, and night sweats. CXR revealed a right upper lobe cavitary lesion. Evaluation was negative for Mycobacterium tuberculosis, and sputum revealed Mycobacterium avium intracellulare (MAI). Since his clinical course was atypical for MAI, further investigations were pursued which identified Mycobacterium interjectum in lung specimens, a...