نتایج جستجو برای: cd117 c

تعداد نتایج: 1057418  

2007
Ana L. Gomes Jorge S. Reis-Filho José M. Lopes Olga Martinho Maryou B. K. Lambros Albino Martins Fernando Schmitt Fernando Pardal Rui M. Reis

Gliomas are the most common and devastating primary brain tumours. Despite therapeutic advances, the majority of gliomas do not respond either to chemo or radiotherapy. KIT, a class III receptor tyrosine kinase (RTK), is frequently involved in tumourigenic processes. Currently, KIT constitutes an attractive therapeutic target. In the present study we assessed the frequency of KIT overexpression...

Journal: :Collegium antropologicum 2015
Snjezana Stemberger-Papić Danijela Vrdoljak-Mozetic Damjana Versa Ostojić Roberta Rubesa-Mihaljević Ines Krigtofić Alemka Brncić-Fisher Maja Kragević Senija Eminović

The cancer stem cells (CSCs) represent a minority of tumor cells that are able to proliferate and self-renew and might be responsible for tumor initiation and maintenance. The CD133 and CD117 are the most commonly used markers for the putative CSCs, especially for the ovarian CSCs, but its clinical significance remains uncertain. The aim of this study was to compare the immunohistochemical expr...

2016
Hyewon Chung Yu-Hwan Kim Myoung Kwon So-Jin Shin Sang-Hoon Kwon Soon-Do Cha Chi-Heum Cho

OBJECTIVE The identification of cancer stem-like cells is a recent development in ovarian cancer. Compared to other cancer cells, cancer stem-like cells present more chemo-resistance and more aggressive characteristics. They play an important role in the recurrence and drug resistance of cancer. Therefore, the target therapy of cancer stem-like cell may become a promising and effective approach...

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